Lactate Dehydrogenase A/LDHA Products

Antibodies
Lactate Dehydrogenase A/LDHA ...
Lactate Dehydrogenase A/LDHA Antibody
Species: Hu, Mu, Po, Bv
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Lactate Dehydrogenase A/LDHA ...
Lactate Dehydrogenase A/LDHA Antib...
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Mouse Monoclonal
Lactate Dehydrogenase A/LDHA ...
Lactate Dehydrogenase A/LDHA Antib...
MAB9158
Species: Hu, Rt
Applications: WB, IHC, ICC
Host: Rabbit Monoclonal
Antibody Pairs
Lactate Dehydrogenase A/LDHA ...
Lactate Dehydrogenase A/LDHA Antib...
H00003939-PW1
Species: Hu
Applications: WB, IP
Kits
Lactate Dehydrogenase A/LDHA ...
Lactate Dehydrogenase A/LDHA Color...
KA0785
Species: Ma
Applications: Func
Lactate Dehydrogenase A/LDHA ...
Lactate Dehydrogenase A/LDHA Color...
KA0786
Species: Ma
Applications: Func
Lysates
Lactate Dehydrogenase A/LDHA ...
Lactate Dehydrogenase A/LDHA Overe...
NBL1-12470
Applications: WB
Lactate Dehydrogenase A/LDHA ...
Lactate Dehydrogenase A/LDHA Overe...
H00003939-T01
Species: Hu
Applications: WB
Proteins
Recombinant Mouse Lactate Deh ...
Recombinant Mouse Lactate Dehydrog...
NBP2-52341
Species: Mu
Applications: Func, PAGE
Lactate Dehydrogenase A/LDHA ...
Lactate Dehydrogenase A/LDHA Block...
NBP1-48336PEP
Species: Hu
Recombinant Human Lactate Deh ...
Recombinant Human Lactate Dehydrog...
9158-HA
Species: Hu
Applications: EnzAct

Description

Lactate dehydrogenase (LDH) is an ubiquitous enzyme commonly found in wide variety of organisms, including plants and microbes. LDH is involved in the interconversion of the pyruvate and NADH to lactate and NAD+. It is also called Hydroxybutyrate Dehydrogenase (HBD), due to the fact that it can catalyze the oxidation of hydroxybutyrate (1). In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C, forming various terameric isoenzymes (140 kDa). Lactate dehydrogenase A (LDH-A, muscle subunit, LDH-M) is involved in the final step of anaerobic glycoysis and catalyzes the conversion of L-lactate and NAD to pryruvate and NADH. While it is predominantly expressed in muscle tissue, it is hormonally regulated in rodents and overexpressed during mammary gland tumorigenesis (2). A mutation that cause deficiency in LDH-A has been implicated in exertional myoglobinuria (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 3939
Alternate Names
  • GSD11
  • EC 1.1.1
  • EC 1.1.1.27
  • proliferation-inducing gene 19
  • LDH muscle subunit
  • lactate dehydrogenase M
  • LDH-M
  • L-lactate dehydrogenase A chain
  • LDH-A
  • Renal carcinoma antigen NY-REN-59
  • LDHM
  • Cell proliferation-inducing gene 19 protein
  • LDH1
  • lactate dehydrogenase A

Research Areas for Lactate Dehydrogenase A/LDHA

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Hypoxia
Lipid and Metabolism
Neuroscience

PTMs for Lactate Dehydrogenase A/LDHA

Learn more about PTMs related to Lactate Dehydrogenase A/LDHA.

Phosphorylation
Oxidation
Carboxylation
Methylation
Acetylation
Reduction
Cleavage
Demethylation
Deacetylation

Bioinformatics Tool for Lactate Dehydrogenase A/LDHA

Discover related pathways, diseases and genes to Lactate Dehydrogenase A/LDHA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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