Kynureninase Products

Antibodies
Kynureninase Antibody (1H1)
Kynureninase Antibody (1H1)
Species: Hu
Applications: IHC, IHC-P
Host: Mouse Monoclonal
Kynureninase Antibody
Kynureninase Antibody
NBP1-56545
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Kynureninase Antibody (771312 ...
Kynureninase Antibody (771312)
MAB7389
Species: Mu
Applications: WB, IHC
Host: Rat Monoclonal
Antibody Pairs
Kynureninase Antibody Pair
Kynureninase Antibody Pair
H00008942-PW1
Species: Hu
Applications: WB, IP
Lysates
Kynureninase Overexpression L ...
Kynureninase Overexpression Lysate...
H00008942-T01
Species: Hu
Applications: WB
Kynureninase Overexpression L ...
Kynureninase Overexpression Lysate...
NBL1-12416
Applications: WB
Proteins
Recombinant Human Kynureninas ...
Recombinant Human Kynureninase Pro...
H00008942-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human Kynureninas ...
Recombinant Human Kynureninase Pro...
H00008942-P01
Species: Hu
Applications: WB, ELISA, PA
Kynureninase Recombinant Prot ...
Kynureninase Recombinant Protein A...
NBP2-14180PEP
Species: Hu
Applications: AC
RNAi
Kynureninase RNAi
Kynureninase RNAi
H00008942-R01
Species: Hu
Applications: RNAi, RNAi SP
Kynureninase RNAi
Kynureninase RNAi
H00008942-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

KYNU, also known as Kynureninase, has a 465 amino acid long isoform that is 52 kDa and a short 307 amino acid that is 35 kDa; its highest expressed levels are found in placenta, liver and lung; is a PLP dependent enzyme that catalyses the cleavage of kynurenine (Kyn) into anthranilic acid (Ant), and It can also act on 3hKyn (to produce 3hAnt) and some other (3-arylcarbonyl)-alanines, and has cysteine-conjugate-beta-lyase activity. This protein is currently being studied for research on the following diseases and disorders: transient cerebral ischemia, vitamin b deficiency, hydroxykynureninuria, pellagra, cerebritis, ischemia, atopic dermatitis, intrahepatic cholangiocarcinoma, essential hypertension, noma, brain injury, dermatitis, psoriasis cholangiocarcinoma, neurologic diseases, interferon, and neuronitis. Interactions with KYNU protein have been shown to involve 40 proteins including GCK, PIN1, NEDD4L, HSPA9, and ETFA in tryptophan catabolism, metabolism, metabolism of amino acids and derivatives, and NAD metabolism pathways.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 8942
Alternate Names
  • L-kynurenine hydrolase
  • EC 3.7.1.3
  • kynureninase (L-kynurenine hydrolase)
  • kynureninase

Pathways for Kynureninase

View related products by pathway and learn more about each of the pathways below.

Methylation
Membrane Depolarization
Phagocytosis
Immune Response
Tissue Homeostasis
Excretion

PTMs for Kynureninase

Learn more about PTMs related to Kynureninase.

Methylation

Bioinformatics Tool for Kynureninase

Discover related pathways, diseases and genes to Kynureninase. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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