After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.
HAF017). A specific band was detected for Islet-1 at approximately 42 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to nuclei in islet cells. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank">
HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox" target="_blank">
Islet 1 encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
![Western Blot Islet-1 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Islet1_AF1837_Western_Blot_21254.jpg)
![Immunocytochemistry Islet-1 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Islet1_AF1837_Immunocytochemistry__Immunofluorescence_17786.jpg)
![Immunohistochemistry Islet-1 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/af1837_human-islet-1-affinity-purified-polyclonal-ab-immunohistochemistry-2682021152534.jpg)
![Simple Western Islet-1 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Islet1_AF1837_Simple_Western_21249.jpg)
![Immunohistochemistry Islet-1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1837_human-islet-1-affinity-purified-polyclonal-ab-41202410481197.jpg)
