IMPA2 Products

Description

IMPA2, also known as Inositol monophosphatase 2, has a 288 amino acid isoform that is 31 kDa and a short 261 amino acid that is 29 kDa, catalyzes the dephosphoylration of inositol monophosphate and plays an important role in phosphatidylinositol signaling, can use myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates, and serves as possible pharmacological target for lithium Li+ action in brain. Studies are being performed on the relationship of this protein to bipolar disorder, mood disorder, seizures, schizophrenia, febrile seizures, bipolar affective disorder, neisseria meningitides, pneumonia, tuberculosis, neuronitis, schizophrenia and leukemia. The protein has been shown to interact with HERPUD1, TNFRSF1H, INPP1, ISYNA1, and PLCG1 in inositol phosphate metabolism, metabolic pathways and phosphatidylinositol signaling system pathways.

Bioinformatics

Entrez	3613 Human
Uniprot	AAH17176 Human NM_014214 Human NP_055029 Human NP_055029.1 Human O14732 Human
Product By Gene ID	3613
Alternate Names	EC 3.1.3.25 IMP 2 IMP.18P IMPase 2 inosine monophosphatase 2 inositol monophosphatase 2 variant 1 inositol monophosphatase 2 variant 2 inositol monophosphatase 2 inositol(myo)-1(or 4)-monophosphatase 2 Inositol-1(or 4)-monophosphatase 2 Myo-inositol monophosphatase A2

Research Areas for IMPA2

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism