IL-1 RI Products

Antibodies
IL-1 RI Antibody
IL-1 RI Antibody
AF771
Species: Mu
Applications: WB, IHC, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
IL-1 RI Antibody (35730)
IL-1 RI Antibody (35730)
MAB269
Species: Hu
Applications: WB, ELISA(Cap)
Host: Mouse Monoclonal
ELISA Kits
IL-1 RI ELISA Kit [Biotin]
IL-1 RI ELISA Kit [Biotin]
KA2210
Species: Hu
Lysates
IL-1 RI Overexpression Lysate ...
IL-1 RI Overexpression Lysate (Den...
H00003554-T01
Species: Hu
Applications: WB
IL-1 RI Overexpression Lysate ...
IL-1 RI Overexpression Lysate (Den...
H00003554-T02
Applications: WB
Proteins
IL-1 RI Recombinant Protein
IL-1 RI Recombinant Protein
NBP2-52213
Species: Hu
Applications: PAGE
IL-1 RI Recombinant Protein A ...
IL-1 RI Recombinant Protein Antigen
NBP2-48589PEP
Species: Hu
Applications: AC
IL-1 RI Recombinant Protein A ...
IL-1 RI Recombinant Protein Antigen
NBP2-48500PEP
Species: Hu
Applications: AC
RNAi
IL-1 RI RNAi
IL-1 RI RNAi
H00003554-R02
Species: Hu

Description

The Interleukin 1 receptor type I (IL-1R1) belongs to the IL-1 receptor family (1). IL-1R1 binds to IL-1 alpha, IL-1 beta, and interleukin-1 receptor antagonist protein (IL-1RA). IL-1RA regulates IL-1 ligand biological activity by a competitive interaction for IL-1R1. Upon IL-1 stimulation, adaptor molecule MyD88 is first recruited to the IL-1R1-IL1R accessory protein complex, followed by the recruitment of two serine-threonine kinases, IRAK4 and IRAK, and the adaptor protein TRAF6, resulting in activation of the NF-kB pathway (2-3). Stimulation of IL-1R1, leads to activation of the transcription factors NF-B, ATF, and AP-1.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 3554
Alternate Names
  • Interleukin 1 Receptor 1
  • Il1r1
  • IL1R1
  • p80
  • CD121a antigen
  • CD121 antigen-like family member A
  • IL1RT1
  • IL1R
  • interleukin-1 receptor type 1
  • IL-1RT1
  • interleukin receptor 1
  • IL-1RT-1
  • interleukin 1 receptor, type I

Research Areas for IL-1 RI

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cytokine Research
Immunology
Innate Immunity
Phospho-Specific

PTMs for IL-1 RI

Learn more about PTMs related to IL-1 RI.

Cleavage
Phosphorylation
Ubiquitination
Glycosylation

Bioinformatics Tool for IL-1 RI

Discover related pathways, diseases and genes to IL-1 RI. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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