IL-1 RI Products

Antibodies
IL-1 RI Antibody [Unconjugate ...
IL-1 RI Antibody [Unconjugated]
AF771
Species: Mu
Applications: WB, IHC, B/N
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
IL-1 RI Antibody (40101)
IL-1 RI Antibody (40101)
NBP1-50304
Species: Hu, Sh
Applications: WB, ELISA, IHC, IHC-P, RI, RIA, WB (-)
Host: Mouse Monoclonal
Antibody Pairs
IL-1 RI Antibody Pair [HRP]
IL-1 RI Antibody Pair [HRP]
NBP2-79665
Species: Hu
Applications: S-ELISA
Conjugate Catalog # Availability Size Price
IL-1 RI Antibody Pair [HRP]
IL-1 RI Antibody Pair [HRP]
NBP2-79625
Species: Rt
Applications: S-ELISA
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
IL-1 RI Antibody Pair [HRP]
IL-1 RI Antibody Pair [HRP]
NBP2-79604
Species: Mu
Applications: S-ELISA
Host: Rabbit
Conjugate Catalog # Availability Size Price
ELISA Kits
Human IL-1 RI DuoSet ELISA, 1 ...
Human IL-1 RI DuoSet ELISA, 15 Plate
DY269
Species: Hu
Applications: ELISA
Mouse IL-1 RI DuoSet ELISA, 5 ...
Mouse IL-1 RI DuoSet ELISA, 5 Plate
DY771-05
Species: Mu
Applications: ELISA
Rat IL-1 RI ELISA Kit (Colori ...
Rat IL-1 RI ELISA Kit (Colorimetric)
NBP2-80382
Species: Rt
Applications: ELISA, S-ELISA
Lysates
IL-1 RI 293T Cell Transient O ...
IL-1 RI 293T Cell Transient Overex...
H00003554-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human IL-1 RI Pro ...
Recombinant Human IL-1 RI Protein
269-1R
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse IL-1 RI Fc ...
Recombinant Mouse IL-1 RI Fc Chime...
771-MR
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Rat IL-1 RI Fc Ch ...
Recombinant Rat IL-1 RI Fc Chimera...
4895-MR
Species: Rt
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

The Interleukin 1 receptor type I (IL-1R1) belongs to the IL-1 receptor family (1). IL-1R1 binds to IL-1 alpha, IL-1 beta, and interleukin-1 receptor antagonist protein (IL-1RA). IL-1RA regulates IL-1 ligand biological activity by a competitive interaction for IL-1R1. Upon IL-1 stimulation, adaptor molecule MyD88 is first recruited to the IL-1R1-IL1R accessory protein complex, followed by the recruitment of two serine-threonine kinases, IRAK4 and IRAK, and the adaptor protein TRAF6, resulting in activation of the NF-kB pathway (2-3). Stimulation of IL-1R1, leads to activation of the transcription factors NF-B, ATF, and AP-1.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 3554
Alternate Names
  • Interleukin 1 Receptor 1
  • Il1r1
  • IL1R1
  • p80
  • CD121a antigen
  • CD121 antigen-like family member A
  • IL1RT1
  • IL1R
  • interleukin-1 receptor type 1
  • IL-1RT1
  • interleukin receptor 1
  • IL-1RT-1
  • interleukin 1 receptor, type I

Research Areas for IL-1 RI

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cytokine Research
Immunology
Innate Immunity
Phospho-Specific

PTMs for IL-1 RI

Learn more about PTMs related to IL-1 RI.

Cleavage
Phosphorylation
Ubiquitination
Glycosylation

Bioinformatics Tool for IL-1 RI

Discover related pathways, diseases and genes to IL-1 RI. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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