IgM Products

Antibodies
ELISA Kits
IgM ELISA Kit [HRP]
IgM ELISA Kit [HRP]
KA1014
Species: Mu
IgM ELISA Kit [HRP]
IgM ELISA Kit [HRP]
KA2040
Species: Rb
IgM ELISA Kit [HRP]
IgM ELISA Kit [HRP]
KA2039
Species: Po
Isotype Controls
Mouse IgM Isotype Control (MM ...
Mouse IgM Isotype Control (MM-30) ...
NBP2-27282
Species: Mu
Applications: Flow, ICC/IF
Host: Mouse Monoclonal
Rabbit IgM Isotype Control
Rabbit IgM Isotype Control
NBP1-96968
Species: Rb
Applications: WB, ELISA, IHC, IHC-P, IP, PAGE
Rat IgM Isotype Control
Rat IgM Isotype Control
NBP1-96776
Species: Rt
Applications: WB, ELISA, IHC, IHC-P, PAGE
Lysates
IgM Overexpression Lysate (De ...
IgM Overexpression Lysate (Denatured)
H00003507-T01
Species: Hu
Applications: WB
Proteins
IgM Recombinant Protein
IgM Recombinant Protein
H00003507-P01
Species: Hu
Applications: WB, ELISA, PA
Secondary Antibodies
Goat anti-Chicken IgM Seconda ...
Goat anti-Chicken IgM Secondary An...
NB7278
Species: Ch
Applications: ICC/IF, IHC, IHC-P
Host: Goat Polyclonal
Goat anti-Mouse IgM Secondary ...
Goat anti-Mouse IgM Secondary Anti...
NB7497
Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Goat Polyclonal
Goat anti-Chicken IgM Seconda ...
Goat anti-Chicken IgM Secondary An...
NB7276
Species: Ch
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Goat Polyclonal

Description

IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to its large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to its high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. IgM measurement yields information about the body's immediate resistance and response to infection as well as information related to specific diseases. Decreased levels are associated with immune deficiency states, hereditary deficiencies, and myeloma. Increased levels can be associated with Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease.

Bioinformatics

Entrez Human
Uniprot Human
Mouse
Product By Gene ID 3507
Alternate Names
  • MGC52291
  • AGM1
  • VH
  • DKFZp686I15212
  • DKFZp686I15196
  • FLJ00385
  • MGC104996
  • MU
  • immunoglobulin heavy constant mu

Research Areas for IgM

Find related products by research area and learn more about each of the different research areas below.

Immunology

Bioinformatics Tool for IgM

Discover related pathways, diseases and genes to IgM. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related IgM Blog Posts

Check out the latest blog posts on IgM.
Understanding the Importance of Human IgG
Human IgG is a component of the immune system that protects the body from infection. It is the most abundantly found antibody isotype within the circulatory system of the human body. All antibody isotypes contain two heavy chains and two light chains...    Read more.
Read more IgM related blogs.