IgM Products

Antibodies
IgM Antibody (II/41)
IgM Antibody (II/41)
Species: Mu
Applications: ELISA, Flow, IHC, IHC-Fr
Host: Rat Monoclonal
ELISA Kits
Mouse IgM ELISA Kit (Colorime ...
Mouse IgM ELISA Kit (Colorimetric)
NBP2-61294
Species: Mu
Applications: ELISA
Human IgM ELISA Kit (Colorime ...
Human IgM ELISA Kit (Colorimetric)
NBP2-60477
Species: Hu
Applications: ELISA
Canine IgM ELISA Kit
Canine IgM ELISA Kit
KA1958
Species: Ca
Applications: ELISA
Isotype Controls
Monkey IgM Isotype Control
Monkey IgM Isotype Control
NBP1-97060
Species: Mk
Applications: WB, ELISA, IHC, IHC-Fr, IHC-P, PAGE
Sheep IgM Isotype Control
Sheep IgM Isotype Control
NBP1-96774
Species: Sh
Applications: WB, ELISA, IHC, IHC-Fr, IHC-P, IP, PAGE
Mouse IgM Isotype Control (MM ...
Mouse IgM Isotype Control (MML)
NBP1-96976
Species: Mu
Applications: WB, ELISA, FLISA, Flow, ICC/IF, IP, PAGE
Host: Mouse Monoclonal
Lysates
IgM Overexpression Lysate (De ...
IgM Overexpression Lysate (Denatured)
H00003507-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human IgM Protein ...
Recombinant Human IgM Protein
H00003507-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP
Secondary Antibodies
Goat anti-Chicken IgM Seconda ...
Goat anti-Chicken IgM Secondary An...
NB7276
Species: Ch
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Goat anti-Mouse IgM Secondary ...
Goat anti-Mouse IgM Secondary Anti...
NB7494
Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price

Description

IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to its large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to its high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. IgM measurement yields information about the body's immediate resistance and response to infection as well as information related to specific diseases. Decreased levels are associated with immune deficiency states, hereditary deficiencies, and myeloma. Increased levels can be associated with Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease.

Bioinformatics

Entrez Human
Uniprot Human
Mouse
Product By Gene ID 3507
Alternate Names
  • MGC52291
  • AGM1
  • VH
  • DKFZp686I15212
  • DKFZp686I15196
  • FLJ00385
  • MGC104996
  • MU
  • immunoglobulin heavy constant mu

Research Areas for IgM

Find related products by research area and learn more about each of the different research areas below.

Immunology

Bioinformatics Tool for IgM

Discover related pathways, diseases and genes to IgM. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related IgM Blog Posts

Check out the latest blog posts on IgM.
How to identify B cell subsets using flow cytometry
By Victoria OsinskiUsing flow cytometry to identify B cell subsetsIdentifying cellular subsets by flow cytometry requires careful and thorough planning in order to ensure the correct subset of cells are identified a...    Read more.
Understanding the Importance of Human IgG
Human IgG is a component of the immune system that protects the body from infection. It is the most abundantly found antibody isotype within the circulatory system of the human body. All antibody isotypes contain two heavy chains and two light chains...    Read more.
Read more IgM related blogs.