HSD3B1 Products

Description

3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase (HSD3B1) is a bifunctional enzyme involved in the oxidative conversion of steroids and plays an important role in the synthesis of all steroid hormones. There are two HSD3B1 proteins--designated type I and type II--that are expressed by different genes and function in different areas of the body. HSD3B1 has also been shown to be a highly specific and sensitive trophoblast-associated marker.

HSD3B1 is required for the production of progesterone by the placenta, so it is predicted that mutations in this gene may cause infertility in women. HSD3B1 antibodies are useful tools for researchers studying hormone regulation and reproductive biology.

Bioinformatics

Entrez	3283 Human
Uniprot	AAH31999 Human AAH31999.1 Human NM_000862 Human P14060 Human NP_000853.1 Human
Product By Gene ID	3283
Alternate Names	EC 1.1.1 3BETAHSD 3BH 3-beta-hydroxy-Delta(5)-steroid dehydrogenase steroid Delta-isomerase short chain dehydrogenase/reductase family 11E, member 1,3-beta-hydroxy-5-ene steroid dehydrogenase 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 progesterone reductase HSDB3A hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1 3-beta-HSD I delta-5-3-ketosteroid isomerase 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I I Trophoblast antigen FDO161G HSDB3 SDR11E1 HSD3B hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

Diseases related to HSD3B1

Discover more about diseases related to HSD3B1.

Malignant Neoplasms
Malignant Neoplasm Of Prostate
Hypertensive Disease
Prostatic Neoplasms
Hyperplasia
Virilism
Congenital Adrenal Hyperplasia
Neoplasms
Adrenal Hyperplasia
Cholangiocarcinoma
Essential Hypertension
Disorders Of Sex Development
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Mammary Neoplasms
Neoplasms, Hormone-dependent
Adenocarcinoma
Congenital Abnormality
Malignant Paraganglionic Neoplasm

Pathways for HSD3B1

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Secretion
Cell Proliferation
Luteinization
Pathogenesis
Localization
Sex Differentiation
Transport
Translation
Progesterone Secretion
Spermatogenesis
Cell Differentiation
Dna Methylation
Ovulation
Reverse Transcription
Cell Cycle
Hormone Secretion
Cell Development
Methylation
Androstenedione Secretion
Cell Migration

Research Areas for HSD3B1

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Cancer
Lipid and Metabolism
Prostate Cancer
Signal Transduction

PTMs for HSD3B1

Learn more about PTMs related to HSD3B1.

Cleavage
Oxidation
Methylation
Phosphorylation
Ubiquitination

Bioinformatics Tool for HSD3B1

Discover related pathways, diseases and genes to HSD3B1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.