HSD3B1 Products

Description

3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase (HSD3B1) is a bifunctional enzyme involved in the oxidative conversion of steroids and plays an important role in the synthesis of all steroid hormones. There are two HSD3B1 proteins--designated type I and type II--that are expressed by different genes and function in different areas of the body. HSD3B1 has also been shown to be a highly specific and sensitive trophoblast-associated marker.

HSD3B1 is required for the production of progesterone by the placenta, so it is predicted that mutations in this gene may cause infertility in women. HSD3B1 antibodies are useful tools for researchers studying hormone regulation and reproductive biology.

Bioinformatics

Entrez	3283 Human
Uniprot	AAH31999 Human AAH31999.1 Human NM_000862 Human NP_000853.1 Human P14060 Human
Product By Gene ID	3283
Alternate Names	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I 3-beta-HSD I 3BETAHSD 3-beta-hydroxy-Delta(5)-steroid dehydrogenase 3BH delta-5-3-ketosteroid isomerase EC 1.1.1 HSD3B HSDB3 HSDB3A hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1 I progesterone reductase SDR11E1 short chain dehydrogenase/reductase family 11E, member 1,3-beta-hydroxy-5-ene steroid dehydrogenase steroid Delta-isomerase Trophoblast antigen FDO161G

Research Areas for HSD3B1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Lipid and Metabolism
Prostate Cancer
Signal Transduction