HSD17B8 Products

Description

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq]

Bioinformatics

Entrez	7923 Human
Uniprot	AAH08185 Human NM_014234 Human NP_055049 Human NP_055049.1 Human
Product By Gene ID	7923
Alternate Names	Ke-6,17-beta-hydroxysteroid dehydrogenase 8 EC 1.1.1.63,17-beta-HSD 8 Testosterone 17-beta-dehydrogenase 8 EC 1.1.1.62 Really interesting new gene 2 protein EC 1.1.1.- Protein Ke6 short chain dehydrogenase/reductase family 30C, member 1 SDR30C1 ke-6 KE6 estrogen 17-oxidoreductase H2-KE6 FABGLestradiol 17-beta-dehydrogenase 8 D6S2245EdJ1033B10.9 RING2FABG HKE6FabG (beta-ketoacyl-[acyl-carrier-protein] reductase, E coli) like (E. coli) hydroxysteroid (17-beta) dehydrogenase 8,3-oxoacyl-[acyl-carrier-protein] reductase

Diseases related to HSD17B8

Discover more about diseases related to HSD17B8.

Neoplasm Metastasis
Neoplasms
Malignant Squamous Cell Neoplasm
Malignant Neoplasms
Head And Neck Neoplasms
Metastatic Malignant Neoplasm To The Lymph Node
Liver Carcinoma
Colorectal Neoplasms
Head And Neck Carcinoma
Tissue Adhesions
Colorectal Cancer
Carcinoma

Pathways for HSD17B8

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Transport
Cell Adhesion
Cell Cycle

Bioinformatics Tool for HSD17B8

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