HLA DMA Products

Antibodies
HLA DMA Antibody
HLA DMA Antibody
H00003108-D01P
Species: Hu, Mu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Antibody Pairs
HLA DMA Antibody Pair
HLA DMA Antibody Pair
H00003108-PW1
Species: Hu
Applications: WB, IP
Lysates
HLA DMA Overexpression Lysate ...
HLA DMA Overexpression Lysate (Den...
H00003108-T01
Species: Hu
Applications: WB
HLA DMA Overexpression Lysate ...
HLA DMA Overexpression Lysate (Nat...
NBL1-11591
Applications: WB
Proteins
HLA DMA Recombinant Protein
HLA DMA Recombinant Protein
H00003108-P01
Species: Hu
Applications: WB, ELISA, PA
HLA DMA Recombinant Protein A ...
HLA DMA Recombinant Protein Antigen
NBP1-85325PEP
Species: Hu
Applications: AC
RNAi
HLA DMA RNAi
HLA DMA RNAi
H00003108-R02
Species: Hu

Description

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 3108
Alternate Names
  • DMA
  • HLA class II histocompatibility antigen, DM alpha chain
  • Really interesting new gene 6 protein
  • class II histocompatibility antigen, M alpha chain
  • D6S222E
  • RING6HLADM
  • MHC class II antigen DMA
  • major histocompatibility complex, class II, DM alpha

Pathways for HLA DMA

View related products by pathway and learn more about each of the pathways below.

Transport
Pathogenesis
Drug Resistance
Intracellular Transport
Cell Cycle
Glycosylation
Response To Nematode
Endocytosis
Protein Ubiquitination

Research Areas for HLA DMA

Find related products by research area and learn more about each of the different research areas below.

Asthma
Diabetes Research
Immunology

PTMs for HLA DMA

Learn more about PTMs related to HLA DMA.

Glycosylation

Bioinformatics Tool for HLA DMA

Discover related pathways, diseases and genes to HLA DMA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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