HDAC5 Products

Antibodies
HDAC5 Antibody
HDAC5 Antibody
NBP2-22152
Species: Hu, Mu, Pm
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HDAC5 Antibody
HDAC5 Antibody
NBP2-03988
Species: Hu, Mu
Applications: WB, ChIP, IP
Host: Rabbit Polyclonal
HDAC5 [p Ser498] Antibody
HDAC5 [p Ser498] Antibody
NB100-81953
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
HDAC5 Overexpression Lysate ( ...
HDAC5 Overexpression Lysate (Native)
NBL1-11483
Applications: WB
Proteins
HDAC5 Partial Recombinant Pro ...
HDAC5 Partial Recombinant Protein
H00010014-Q01
Species: Hu
Applications: WB, ELISA, PA
HDAC5 Recombinant Protein Ant ...
HDAC5 Recombinant Protein Antigen
NBP1-83436PEP
Species: Hu
Applications: AC
RNAi
HDAC5 RNAi
HDAC5 RNAi
H00010014-R02
Species: Hu
Applications: RNAi, RNAi SP
HDAC5 RNAi
HDAC5 RNAi
H00010014-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF(p300/CBP- associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 10014
Alternate Names
  • KIAA0600
  • EC 3.5.1.98
  • NY-CO-9
  • HD5
  • FLJ90614
  • Antigen NY-CO-9
  • histone deacetylase 5

Research Areas for HDAC5

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Cell Cycle and Replication
Chromatin Research
Epigenetics
Histone Deacetylases
Phospho-Specific

Bioinformatics Tool for HDAC5

Discover related pathways, diseases and genes to HDAC5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related HDAC5 Blog Posts

Check out the latest blog posts on HDAC5.
SREBP2: From Cholesterol Homeostasis to Cancer Invasion
Sterol-regulatory-element-binding protein 2 (SREBP2) is a transcription factor that regulates cholesterol homeostasis by controlling enzymes involved in cholesterol synthesis and uptake, e.g. HMG-CoA. Along with another transcription factor LXR, SREBP...    Read more.
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