Species: Hu, Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
WB, Flow, IHC, CyTOF-ready, ICC/IFHost:
Hu, Mu, RtApplications:
WB, Flow, CyTOF-ready, ICC/IFHost:
The Glypican 3 (GPC3) gene encodes for a member of the glypican-related integral membrane proteoglycan family (GRIPS). Two isoforms of the protein exist, isoform 1 at a length of 580 amino acids long and 65 kDA while isoform 2 is 526 amino acids long at 59 kDA. The protein encoded by GPC3 is thought to prevent the dipeptidyl peptidase activity of DPP4 and may participate in the suppression and regulation of growth in the predominately mesodermal tissues and organs. The GPC3 gene participates in the Wnt signaling pathway, metabolism, and visual phototransduction through interactions with genes FGF2, WNT3A, WNT7B, BCAN, and BGN. GPC3 has been researched in various diseases such as paine syndrome, horner's sundrome, liver cirrhosis, simpson-golabi-behmel syndrome, germ cell tumors, wilms tumors, complex regional pain syndrome, and hepatocellulcar carcinoma.
|Product By Gene ID
- Intestinal protein OCI-5
- secreted glypican-3
- heparan sulphate proteoglycan
- glypican proteoglycan 3
- glypican 3
Bioinformatics Tool for Glypican 3
Discover related pathways, diseases and genes to Glypican 3. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.