GFR alpha-2/GDNF R alpha-2 Products

Antibodies
GFR alpha-2/GDNF R alpha-2 An ...
GFR alpha-2/GDNF R alpha-2 Antibod...
AF429
Species: Hu, Mu
Applications: WB, IHC, Block
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
GFR alpha-2/GDNF R alpha-2 An ...
GFR alpha-2/GDNF R alpha-2 Antibod...
AF613
Species: Hu
Applications: WB, IHC, Block
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
GFR alpha-2/GDNF R alpha-2 An ...
GFR alpha-2/GDNF R alpha-2 Antibody
NBP1-77042
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
GFR alpha-2/GDNF R alpha-2 Ov ...
GFR alpha-2/GDNF R alpha-2 Overexp...
NBL1-11052
Applications: WB
Proteins
GFR alpha-2/GDNF R alpha-2 Re ...
GFR alpha-2/GDNF R alpha-2 Recombi...
NBP1-89778PEP
Species: Hu
Applications: AC
GFR alpha-2/GDNF R alpha-2 Pe ...
GFR alpha-2/GDNF R alpha-2 Peptide
NBP1-77042PEP
Species: Hu
Applications: AC
RNAi
GFR alpha-2/GDNF R alpha-2 RN ...
GFR alpha-2/GDNF R alpha-2 RNAi
H00002675-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Members of the glial cell line derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRa, which is a cell surface receptor for NTN. The cDNAs encoding NTNRa from human, rat, chicken, and mouse have been cloned recently. NTNRa was also termed GDNFRb, Ret ligand 2 (RETL2) or TGFb related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRa2 recently. GFRa2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 2675
Alternate Names
  • NRTNR-alpha
  • GDNF receptor alpha-2
  • TRN receptor, GPI-anchored
  • NTNR-alpha
  • TGF-beta related neurotrophic factor receptor 2
  • GFR-alpha-2
  • PI-linked cell-surface accessory protein
  • GDNFR-beta
  • glial cell line derived neurotrophic factor receptor, beta
  • GDNFR-alpha-2
  • GFR-alpha 2
  • Neurturin receptor alpha
  • GDNF family receptor alpha-2
  • NTNRA
  • TRNR2NRTNR-ALPHA
  • RETL2TGF-beta-related neurotrophic factor receptor 2
  • GDNFRBRET ligand 2
  • GDNF receptor beta
  • GDNF family receptor alpha 2

Research Areas for GFR alpha-2/GDNF R alpha-2

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Immunology

PTMs for GFR alpha-2/GDNF R alpha-2

Learn more about PTMs related to GFR alpha-2/GDNF R alpha-2.

Phosphorylation
Reduction

Bioinformatics Tool for GFR alpha-2/GDNF R alpha-2

Discover related pathways, diseases and genes to GFR alpha-2/GDNF R alpha-2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.