GFR alpha-1/GDNF R alpha-1 Products

Antibodies
GFR alpha-1/GDNF R alpha-1 An ...
GFR alpha-1/GDNF R alpha-1 Antibod...
AF560
Species: Rt
Applications: WB, IHC, Block
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
GFR alpha-1/GDNF R alpha-1 An ...
GFR alpha-1/GDNF R alpha-1 Antibody
AF714
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
GFR alpha-1/GDNF R alpha-1 An ...
GFR alpha-1/GDNF R alpha-1 Antibod...
MAB560
Species: Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Lysates
GFR alpha-1/GDNF R alpha-1 Ov ...
GFR alpha-1/GDNF R alpha-1 Overexp...
NBP2-05472
Applications: WB
GFR alpha-1/GDNF R alpha-1 Ov ...
GFR alpha-1/GDNF R alpha-1 Overexp...
NBP2-11349
Applications: WB
GFR alpha-1/GDNF R alpha-1 Ov ...
GFR alpha-1/GDNF R alpha-1 Overexp...
NBP2-10479
Applications: WB
Proteins
GFR alpha-1/GDNF R alpha-1 Pa ...
GFR alpha-1/GDNF R alpha-1 Partial...
H00002674-Q01
Species: Hu
Applications: WB, ELISA, PA
GFR alpha-1/GDNF R alpha-1 Re ...
GFR alpha-1/GDNF R alpha-1 Recombi...
H00002674-P01
Species: Hu
Applications: WB, ELISA, PA
GFR alpha-1/GDNF R alpha-1 Re ...
GFR alpha-1/GDNF R alpha-1 Recombi...
NBP2-14045PEP
Species: Hu
Applications: AC
RNAi
GFR alpha-1/GDNF R alpha-1 RN ...
GFR alpha-1/GDNF R alpha-1 RNAi
H00002674-R03
Species: Hu
Applications: RNAi, RNAi SP
GFR alpha-1/GDNF R alpha-1 RN ...
GFR alpha-1/GDNF R alpha-1 RNAi
H00002674-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRalpha, which is a cell surface receptor for GDNF (1,2). The cDNAs encoding GDNFRalpha from human, rat, chicken and mouse have been cloned recently (1-5). GDNFRalpha was also termed Ret ligand 1 (RETL1) or TGF-beta-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRalpha-1 recently (5-7). GFRalpha-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRalpha and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 2674
Alternate Names
  • DKFZp313E1012
  • GFR-alpha-1
  • TGF-beta-related neurotrophic factor receptor 1
  • TGF-beta related neurotrophic factor receptor 1
  • RET ligand 1
  • PI-linked cell-surface accessory protein
  • GDNF receptor alpha-1
  • GPI-linked anchor protein
  • GDNFR-alpha-1
  • Glial cell line-derived neurotrophic factor receptor alpha
  • RET1L
  • GDNF family receptor alpha-1
  • GDNFRAGFR-ALPHA-1
  • GDNFRMGC23045
  • TRNR1FLJ31546
  • RETL1FLJ10561
  • DKFZp686J0156
  • GDNF family receptor alpha 1

Research Areas for GFR alpha-1/GDNF R alpha-1

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Signal Transduction

PTMs for GFR alpha-1/GDNF R alpha-1

Learn more about PTMs related to GFR alpha-1/GDNF R alpha-1.

Phosphorylation
Reduction
Biotinylation
Phosphorothioation
Glycosylation
Acetylation
Methylation
Ubiquitination

Bioinformatics Tool for GFR alpha-1/GDNF R alpha-1

Discover related pathways, diseases and genes to GFR alpha-1/GDNF R alpha-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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