FA2H Products

FA2H Overexpression Lysate
FA2H Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human FA2H Protei ...
Recombinant Human FA2H Protein
Species: Hu
Applications: WB, ELISA, PA, AP
FA2H Recombinant Protein Anti ...
FA2H Recombinant Protein Antigen
Species: Hu
Applications: AC
FA2H Recombinant Protein Anti ...
FA2H Recombinant Protein Antigen
Species: Hu
Applications: AC


Sphingolipids are a large class of lipids found in all eukaryotic cells and are involved in numerous cellular processes. The structural diversity of sphingolipids stems from more than 300 distinct head groups, as well as from modifications of the hydrophobic ceramide moiety. FA2H catalyzes a common modification of the ceramide moiety: hydroxylation at the 2 position of the N-acyl chain. Sphingolipids containing 2-hydroxy fatty acid are common in nervous and epidermal tissue. Glycosphingolipids containing a high proportion of 2-hydroxy fatty acid are critical components of myelin, and several very long chain ceramides with 2-hydroxy fatty acids are important for the permeability barrier function of epidermis (Alderson et al., 2004 [PubMed 15337768]).[supplied by OMIM]


Entrez Human
Uniprot Human
Product By Gene ID 79152
Alternate Names
  • Fatty acid alpha-hydroxylase
  • spastic paraplegia 35 (autosomal recessive)
  • SPG35
  • fatty acid hydroxylase domain containing 1
  • SCS7
  • FLJ25287
  • FAH1
  • fatty acid 2-hydroxylase

Research Areas for FA2H

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Lipid and Metabolism

PTMs for FA2H

Learn more about PTMs related to FA2H.


Bioinformatics Tool for FA2H

Discover related pathways, diseases and genes to FA2H. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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