Erbin Products

Description

This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date.

Bioinformatics

Entrez	55914 Human
Uniprot	NP_061165 Human
Product By Gene ID	55914
Alternate Names	Densin-180-like protein erbb2 interacting protein Erbb2-interacting proteinErbin ERBB2IP Erbin ERBINLAP2protein LAP2 KIAA1225