EphB4 Products

EphB4 Antibody
EphB4 Antibody
Species: Mu
Applications: WB, Flow, IHC, CyTOF-ready
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
EphB4 Antibody [Unconjugated] ...
EphB4 Antibody [Unconjugated]
Species: Hu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready, KO
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
EphB4 Knockout 293T Cell Lysa ...
EphB4 Knockout 293T Cell Lysate
Species: Hu
Applications: WB
EphB4 Overexpression Lysate ( ...
EphB4 Overexpression Lysate (Native)
Species: Hu
Applications: WB
Recombinant Mouse EphB4 Fc Ch ...
Recombinant Mouse EphB4 Fc Chimera...
Species: Mu
Applications: Binding Activity
Formulation Catalog # Availability Price  
Recombinant Human EphB4 Prote ...
Recombinant Human EphB4 Protein, CF
Species: Hu
Applications: Binding Activity
Formulation Catalog # Availability Price  
Recombinant Mouse EphB4 Prote ...
Recombinant Mouse EphB4 Protein
Species: Mu
Applications: PAGE
EphB4 RNAi
EphB4 RNAi
Species: Hu
Applications: RNAi, RNAi SP


EphB4, also known as Htk, Myk1, Tyro11, and Mdk2, is a member of the Eph receptor family, which binds of the ephrin ligand family. Two classes of receptors exist, designated A and B, that have an extracellular domain made up of a globular domain, a cysteine-rich domain, and two fibronectin type III domains, followed by the transmembrane region and cytoplasmic region. The cytoplasmic region contains juxtamembrane motif with two tyrosines, which are the major autophosphorylation sites, along with a kinase domain, and a conserved sterile alpha motif (SAM) in the carboxyl terminus, which includes one conserved tyrosine. Ligand recognition and binding leads to activation of intrinsic kinase activity. Only membrane-bound or Fc-clustered ligands have been shown to activate the receptor in vitro. Soluble monomeric ligands can bind the receptor, but do not induce receptor autophosphorylation and activation. The Eph receptors and ephrin ligands display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands.Ephs and ephrins play a significant role in angiogenesis.


Entrez Human
Uniprot Human
Product By Gene ID 2050
Alternate Names
  • EC 2.7.10
  • EphB4
  • soluble EPHB4 variant 3
  • MYK1
  • soluble EPHB4 variant 2
  • EC
  • soluble EPHB4 variant 1
  • TYRO11
  • hepatoma transmembrane kinase
  • Tyrosine-protein kinase TYRO11
  • ephrin type-B receptor 4
  • Tyrosine-protein kinase receptor HTK
  • HTKephrin receptor EphB4
  • Tyro11
  • EPH receptor B4

Research Areas for EphB4

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

PTMs for EphB4

Learn more about PTMs related to EphB4.


Bioinformatics Tool for EphB4

Discover related pathways, diseases and genes to EphB4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related EphB4 Blog Posts

Check out the latest blog posts on EphB4.
Vimentin: Regulating EMT and Cancer
Vimentin, a member of the intermediate filament (IF) family, is a protein responsible for maintaining cellular integrity and reducing damage caused by stress. The vimentin protein is ubiquitously expressed in normal mesenchymal cells, and recent resea...    Read more.
Read more EphB4 related blogs.