DNAJC3 Products

Antibodies
DNAJC3 Antibody
DNAJC3 Antibody
NBP2-48704
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DNAJC3 Antibody
DNAJC3 Antibody
NBP2-16195
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DNAJC3 Antibody
DNAJC3 Antibody
NBP2-48734
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
DNAJC3 Overexpression Lysate ...
DNAJC3 Overexpression Lysate (Native)
NBP2-07649
Applications: WB
Proteins
Recombinant Human DNAJC3 Prot ...
Recombinant Human DNAJC3 Protein
H00005611-P01
Species: Hu
Applications: WB, ELISA, PA
DNAJC3 Recombinant Protein An ...
DNAJC3 Recombinant Protein Antigen
NBP2-48734PEP
Species: Hu
Applications: AC
DNAJC3 Recombinant Protein An ...
DNAJC3 Recombinant Protein Antigen
NBP2-48704PEP
Species: Hu
Applications: AC
RNAi
DNAJC3 RNAi
DNAJC3 RNAi
H00005611-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The 58-kDa inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a cellular protein that is activated during influenza virus infection to down-regulate the activity of PKR. The 58-kDa inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a cellular protein that is activated during influenza virus infection to down-regulate the activity of PKR (1). The P58 protein inhibits both the autophosphorylation of PKR and the phosphorylation of the PKR natural substrate, the alpha subunit of eukaryotic initiation factor eIF-2. Sequence analysis revealed that P58 is a member of the tetratricopeptide family of proteins (2). Also, like other J-domain proteins, P58 stimulated the ATPase activity of Hsc70. Taken together, data suggests that P58 is a co-chaperone, possibly directing hsp/Hsc70 to refold, and thus inhibit kinase function (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 5611
Alternate Names
  • Interferon-induced, double-stranded RNA-activated protein kinase inhibitor
  • protein-kinase, interferon-inducible double stranded RNA dependent inhibitor
  • HP58
  • PRKRIdnaJ homolog subfamily C member 3
  • P58FLJ21288
  • P58IPKProtein kinase inhibitor p58
  • Protein kinase inhibitor of 58 kDa
  • DnaJ (Hsp40) homolog, subfamily C, member 3

Research Areas for DNAJC3

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Golgi Apparatus Markers
Lipid and Metabolism
Unfolded Protein Response

PTMs for DNAJC3

Learn more about PTMs related to DNAJC3.

Phosphorylation
Cleavage
Oxidation

Bioinformatics Tool for DNAJC3

Discover related pathways, diseases and genes to DNAJC3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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