Species: Hu, Mu
Applications: WB
Host: Mouse Monoclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Diacylglycerol (DAG) influences numerous cell signaling cascades by functioning as an intracellular, allosteric activator of protein kinase C (PKC), and as a potent activator of guanine nucleotide exchange factors. In order to maintain cellular homeostasis, intracellular DAG levels are tightly regulated by diacylglycerol kinases (DGKs, DAGKs), which phosphorylate DAG to phosphatidic acid, thus removing DAG. Human DGK-alpha (80 kDa), -beta (90 kDa), and - gamma (90 kDa) have calcium-binding EF-hand motifs at their N termini and are classified as type I DGKs. Human DGK-delta (130 kDa) and DGK-
Bioinformatics
| Entrez |
Rat
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
9162 |
| Alternate Names |
- DAG kinase iota
- DGK-iota
- DGK-IOTA
- diacylglycerol kinase iota
- diacylglycerol kinase, iota
- Diglyceride kinase iota
- EC 2.7.1.107
|
Research Areas for DGK-iota
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction
