Desmocollin-2 Products

Description

Desmocollin 2 is encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms.

Bioinformatics

Entrez	1824 Human
Uniprot	NM_024422 Human NP_004940 Human NP_004940.1 Human NP_077740 Human NP_077740.1 Human
Product By Gene ID	1824
Alternate Names	ARVD11 Cadherin family member 2 CDHF2DGII/III desmocollin 2 desmocollin-2 Desmocollin-3 Desmosomal glycoprotein II desmosomal glycoprotein II/III Desmosomal glycoprotein III DG2 DSC3DKFZp686I11137