DAP12 Products

Antibodies
DAP12 Antibody (406288) [Unco ...
DAP12 Antibody (406288) [Unconjuga...
MAB5240
Species: Hu
Applications: WB, ICFlow
Host: Mouse Monoclonal
DAP12 Antibody
DAP12 Antibody
NBP1-85313
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
DAP12 Antibody
DAP12 Antibody
NBP1-52376
Species: Hu, Bt, Ca, Eq, Mk, Pm, Rabbit, Sheep
Applications: ELISA, IHC-P
Host: Goat Polyclonal
Lysates
DAP12 Overexpression Lysate ( ...
DAP12 Overexpression Lysate (Native)
NBL1-17483
Applications: WB
DAP12 Overexpression Lysate ( ...
DAP12 Overexpression Lysate (Native)
NBL1-17484
Applications: WB
Proteins
DAP12 Partial Recombinant Pro ...
DAP12 Partial Recombinant Protein
H00007305-Q01
Species: Hu
Applications: WB, ELISA, PA
DAP12 Recombinant Protein Ant ...
DAP12 Recombinant Protein Antigen
NBP1-85313PEP
Species: Hu
Applications: AC
DAP12 Recombinant Protein
DAP12 Recombinant Protein
H00007305-P01
Species: Hu
Applications: WB, ELISA, PA

Description

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 7305
Alternate Names
  • TYRO protein tyrosine kinase-binding protein
  • DNAX-activation protein 12
  • killer activating receptor associated protein
  • Killer-activating receptor-associated protein
  • KARAPPLO-SL
  • DAP12PLOSL
  • KAR-associated protein
  • TYRO protein tyrosine kinase binding protein

Research Areas for DAP12

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Signal Transduction

PTMs for DAP12

Learn more about PTMs related to DAP12.

Phosphorylation
Biotinylation
Cleavage
Ubiquitination

Bioinformatics Tool for DAP12

Discover related pathways, diseases and genes to DAP12. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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