Home » DAP12 Products

We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

Register on R&D Systems

DAP12 Products

Antibodies
DAP12 Antibody - BSA Free
DAP12 Antibody - BSA Free
NBP1-85313
Immunohistochemistry-Paraffin DAP12 Antibody - BSA Free
Immunohistochemistry-Paraffin DAP12 Antibody - BSA Free
Immunohistochemistry-Paraffin DAP12 Antibody - BSA Free
Immunohistochemistry-Paraffin DAP12 Antibody - BSA Free
Immunohistochemistry-Paraffin DAP12 Antibody - BSA Free
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
BSA Free NBP1-85313-25ul
DAP12 Antibody
DAP12 Antibody
NBP1-52376
Immunohistochemistry-Paraffin DAP12 Antibody
Immunohistochemistry-Paraffin DAP12 Antibody
Species: Hu, Bt, Ca, Eq, Pm, Pm, Pm, Rb, Sh
Applications: ELISA, Flow, IHC
Host: Goat Polyclonal
DAP12 Antibody (406209) [Unco ...
DAP12 Antibody (406209) [Unconjuga...
MAB52401
MAB003), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2Secondary Antibody (F0101B) and Rabbit anti-human CD56 PE-conjugated Monoclonal Antibody (FAB24086P). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (1X) (FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer (1X) (FC005). " class="big_lightbox" target="_blank"> Intracellular Staining by Flow Cytometry DAP12 Antibody (406209) [Unconjugated]
Species: Hu
Applications: Flow
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 532 FAB52401X
Allophycocyanin FAB52401A
Biotin FAB52401B
CoraFluor 1 FAB52401CL1
DyLight 350 FAB52401D
DyLight 405 FAB52401E
DyLight 488 FAB52401K
DyLight 550 FAB52401L
DyLight 594 FAB52401M
DyLight 650 FAB52401W
DyLight 680 FAB52401Y
DyLight 755 FAB52401Z
FITC FAB52401F
HRP FAB52401H
Janelia Fluor 525 FAB52401JF525
Janelia Fluor 549 FAB52401I
Janelia Fluor 646 FAB52401J
Janelia Fluor 669 FAB52401JF669
PE FAB52401P
PerCP FAB52401C
mFluor Violet 450 SE FAB52401MFV450
mFluor Violet 500 SE FAB52401MFV500
mFluor Violet 610 SE FAB52401MFV610
Formulation Catalog # Availability Price  
Carrier Free MAB52401-100
Carrier Free MAB52401-SP
Read More
Read More
Read More
See All DAP12 Products
We have 4 DAP12 Antibodies
Lysates
DAP12 Overexpression Lysate
DAP12 Overexpression Lysate
NBL1-17483
Western Blot DAP12 Overexpression Lysate
Species: Hu
Applications: WB
DAP12 Overexpression Lysate
DAP12 Overexpression Lysate
NBL1-17484
Western Blot DAP12 Overexpression Lysate
Species: Hu
Applications: WB
Read More
Read More
See All DAP12 Products
We have 2 DAP12 Lysates
Proteins
Recombinant Human DAP12 GST ( ...
Recombinant Human DAP12 GST (N-Ter...
H00007305-Q01
Other Recombinant Human DAP12 GST (N-Term) Protein
Species: Hu
Applications: WB, ELISA, MA, AP
Recombinant Human DAP12 GST ( ...
Recombinant Human DAP12 GST (N-Ter...
H00007305-P01
Other Recombinant Human DAP12 GST (N-Term) Protein
Species: Hu
Applications: WB, ELISA, MA, AP
DAP12 Recombinant Protein Ant ...
DAP12 Recombinant Protein Antigen
NBP1-85313PEP
Species: Hu
Applications: AC
Read More
Read More
Read More
See All DAP12 Products
We have 3 DAP12 Proteins

Description

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.

Bioinformatics

Entrez
7305
Human
Uniprot
AAH11175
Human
NM_003332
Human
NM_198125
Human
NP_003323.1
Human
O43914
Human
Product By Gene ID 7305
Alternate Names
  • DAP12PLOSL
  • DNAX-activation protein 12
  • KARAPPLO-SL
  • KAR-associated protein
  • killer activating receptor associated protein
  • Killer-activating receptor-associated protein
  • TYRO protein tyrosine kinase binding protein
  • TYRO protein tyrosine kinase-binding protein

Research Areas for DAP12

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Signal Transduction

Related DAP12 Blog Posts

Check out the latest blog posts on DAP12.
Harnessing Natural Killer Cell Activity for Anti-Tumor Immunotherapy
By Victoria Osinski, PhDWhat’s “Natural” About Natural Killer (NK) Cells?For immunologists, the term cytotoxicity often conjures up images of an army of antigen specific CD8+ T cells deploying to ...    Read more.
Read more DAP12 related blogs.