COMT Products

Antibodies
COMT Antibody
COMT Antibody
NBP1-85818
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
COMT Antibody
COMT Antibody
AF7386
Species: Hu
Applications: WB
Host: Sheep Polyclonal
COMT Antibody
COMT Antibody
NB100-41387
Species: Hu
Applications: WB, EIA, ELISA, PEP-ELISA, S-ELISA
Host: Goat Polyclonal
Antibody Pairs
COMT Antibody Pair
COMT Antibody Pair
H00001312-PW1
Species: Hu
Applications: WB, IP
COMT Antibody Pair
COMT Antibody Pair
H00001312-AP11
Species: Hu
Applications: S-ELISA
COMT Antibody Pair
COMT Antibody Pair
H00001312-AP21
Species: Hu
Applications: S-ELISA
Lysates
COMT Overexpression Lysate (D ...
COMT Overexpression Lysate (Denatu...
H00001312-T01
Species: Hu
Applications: WB
COMT Overexpression Lysate (N ...
COMT Overexpression Lysate (Native)
NBL1-09374
Applications: WB
Proteins
COMT Recombinant Protein
COMT Recombinant Protein
H00001312-P01
Species: Hu
Applications: WB, ELISA, PA
COMT Recombinant Protein Anti ...
COMT Recombinant Protein Antigen
NBP1-85818PEP
Species: Hu
Applications: AC
COMT Recombinant Protein
COMT Recombinant Protein
NBC1-22920
Species: Hu
Applications: PAGE
Host: Human
RNAi
COMT RNAi
COMT RNAi
H00001312-R02
Species: Hu
COMT RNAi
COMT RNAi
H00001312-R01
Species: Hu

Description

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. The transcript variants are formed through the use of alternative translation initiation sites and promoters.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 1312
Alternate Names
  • catechol O-methyltransferase
  • EC 2.1.1.6
  • catechol-O-methyltransferase

Research Areas for COMT

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

Bioinformatics Tool for COMT

Discover related pathways, diseases and genes to COMT. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.