Complement C5 Products

Antibodies
Complement C5 Antibody (557)
Complement C5 Antibody (557)
NB110-12179
Species: Hu
Applications: WB, B/N, ELISA, Func
Host: Mouse Monoclonal
Complement C5 Antibody (561)
Complement C5 Antibody (561)
NBP1-60147
Species: Hu
Applications: ELISA, Func, IA
Host: Mouse Monoclonal
Complement C5 Antibody
Complement C5 Antibody
NBP1-84395
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
ELISA Kits
Lysates
Complement C5 Overexpression ...
Complement C5 Overexpression Lysat...
NBP2-10765
Applications: WB
Proteins
Complement C5 Partial Recombi ...
Complement C5 Partial Recombinant ...
H00000727-Q01
Species: Hu
Applications: WB, ELISA, PA
Complement C5 Recombinant Pro ...
Complement C5 Recombinant Protein ...
NBP1-84395PEP
Species: Hu
Applications: AC
Complement C5 Recombinant Pro ...
Complement C5 Recombinant Protein
P4491
Species: Mu
Applications: Func, PAGE
RNAi
Complement C5 RNAi
Complement C5 RNAi
H00000727-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190kDa glycoprotein consisting of a disulphide linked alpha-chain (115kDa) and beta-chain (75kDa). C5 occurs in plasma at about 75mg/L. It is activated via either the classical or the alternative complement pathway, by protoelytic cleavage of C5a (11.5kDa) from the N-terminal of the alpha-chain. C5a is a potent anaphylotoxin and stimulates directed migration of neutrophils, eosinophils, basophils and monocytes. The other fragment, C5b,initiates the assembly of the membrane attack complex that mediates the cytolysis of viral and bacterial pathogens.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Mouse
Product By Gene ID 727
Alternate Names
  • C5
  • complement C5
  • FLJ17816
  • anaphylatoxin C5a analog
  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
  • CPAMD4MGC142298
  • FLJ17822
  • complement component 5

Research Areas for Complement C5

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity
Stem Cell Markers

Bioinformatics Tool for Complement C5

Discover related pathways, diseases and genes to Complement C5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Complement C5 Blog Posts

Check out the latest blog posts on Complement C5.
Complement C3 - the most important protein in the complement system
The complement system is made up of a collection of proteins found in the bloodstream and is comprised of nine major complement proteins; complement C3 is one of them. The complement system is a crucial component of the cellular immune system becau...    Read more.
Read more Complement C5 related blogs.