Claudin-19 Products

Description

The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Bioinformatics

Entrez	149461 Human
Uniprot	AAH30524 Human
Product By Gene ID	149461
Alternate Names	claudin 19 Claudin19 Claudin-19 CLDN19

Research Areas for Claudin-19

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Cytoskeleton Markers
Signal Transduction