Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IP, ChIP
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
CHD8 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD8 has been reported to interact with duplin, a protein involved in the wnt signaling pathway, and CTCF, a protein involved in heterochromatin formation.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
57680 |
| Alternate Names |
- ATP-dependent helicase CHD8
- CHD-8
- chromodomain helicase DNA binding protein 8
- DKFZp686N17164
- duplin
- DUPLIN
- EC 3.6.1
- EC 3.6.1.7
- EC 3.6.4.12
- Helicase with SNF2 domain 1chromodomain-helicase-DNA-binding protein 8
- HELSNF1
- KIAA1564axis duplication inhibitor
|
Research Areas for CHD8
Find related products by research area and learn more about each of the different research areas below.
Wnt Signaling Pathway
