CEBP alpha Products

Description

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. Mutations in this gene are frequently found in acute myeloid leukemia (AML).

Bioinformatics

Entrez	12606 Mouse
Product By Gene ID	1050
Alternate Names	C/EBP alpha C/EBP-alpha CCAAT/enhancer binding protein (C/EBP), alpha CCAAT/enhancer-binding protein alpha CEBP alpha CEBP CEBPA

Research Areas for CEBP alpha

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Transcription Factors and Regulators

Related CEBP alpha Blog Posts

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Transcription Factor Antibodies Used In Landmark Evolutionary Study We at Novus Biologicals offer a full antibody database targeted to transcription factor research. Recently, CEBP antibodieswere used in a research study exploring the evolution of gene regulation in various vertebrates. The results revealed surprising...    Read more.

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