CD45 Products

Antibodies
Lysates
CD45 Overexpression Lysate (N ...
CD45 Overexpression Lysate (Native)
NBL1-14981
Applications: WB
Proteins
CD45 Recombinant Protein
CD45 Recombinant Protein
NBP2-51591
Species: Hu
Applications: PAGE
CD45 Partial Recombinant Prot ...
CD45 Partial Recombinant Protein
H00005788-Q01
Species: Hu
Applications: WB, ELISA, PA
CD45 Recombinant Protein Anti ...
CD45 Recombinant Protein Antigen
NBP1-88103PEP
Species: Hu
Applications: AC
RNAi
CD45 RNAi
CD45 RNAi
H00005788-R03
Species: Hu
Applications: RNAi, RNAi SP
CD45 RNAi
CD45 RNAi
H00005788-R02
Species: Hu
Applications: RNAi, RNAi SP
CD45 RNAi
CD45 RNAi
H00005788-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Mouse
Product By Gene ID 5788
Alternate Names
  • EC 3.1.3.48
  • CD45R
  • T200 leukocyte common antigen
  • B220
  • T200 glycoprotein
  • CD45 antigen
  • receptor-type tyrosine-protein phosphatase C
  • L-CA
  • T200receptor type, c polypeptide
  • LY5
  • protein tyrosine phosphatase, receptor type, C

Bioinformatics Tool for CD45

Discover related pathways, diseases and genes to CD45. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related CD45 Blog Posts

Check out the latest blog posts on CD45.
CD45 - Much more than just a housekeeping protein
CD45, also known as T200 or the Leukocyte Common Antigen (LCA), is encoded by the Protein Tyrosine Phosphatase Receptor type C (PTPRC) gene. The protein is expressed exclusively on cells of the haematopoietic system, and is one of the most abundant le...    Read more.
CD45 Isoforms: Hematopoietic Differentiation, Cancer and Alzheimer's
CD45, also known as protein tyrosine phosphatase, receptor type, C (PTPRC), was originally known as common leukocyte antigen and is a signal transducer involved in many physiological processes such as growth and differentiation, cancer transformation,...    Read more.
Vimentin Antibodies in Rheumatoid Arthritis & Cataracts Research
Vimentin is a 57kDa type III intermediate filament (IF) protein that is the major cytoskeletal component of mesenchymal cells and the first to be expressed during cell differentiation. It plays a significant role in supporting and anchoring the positi...    Read more.
Antibodies In The Differential Diagnosis Of Undifferentiated Tumors
Immunohistochemical testing using antibody panels has a valuable role in cancer diagnosis. Some tumors, especially more malignant ones, tend to lose the appearance of the tissue of origin. However, knowing the tissue of origin assists the physician in...    Read more.
Read more CD45 related blogs.