CD117/c-kit Products

Description

CD117 is a 145 kD immunoglobulin superfamily member, also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with it's ligand is critical for the development of hematopoietic stem cells. The 2B8 antibody does not block c-Kit activity.

Bioinformatics

Product By Gene ID	3815
Alternate Names	CD117 antigen CD117 ckit c-kit EC 2.7.10 EC 2.7.10.1 KIT PBT piebald trait Proto-oncogene c-Kit proto-oncogene tyrosine-protein kinase Kit SCF R SCFR SCFRmast/stem cell growth factor receptor soluble KIT variant 1 Tyrosine-protein kinase Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

Research Areas for CD117/c-kit

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cancer Stem Cells
Cellular Markers
Cytokine Research
Hematopoietic Stem Cell Markers
Immunology
Innate Immunity
Mast Cell Markers
Mesenchymal Stem Cell Markers
Phospho-Specific
Protein Kinase
Signal Transduction
Stem Cell Markers
Tyrosine Kinases

Related CD117/c-kit Blog Posts

Check out the latest blog posts on CD117/c-kit.

Do you see what I see? I c-Kit The c-Kit (CD117) proto-oncogene is a 145 kD receptor tyrosine kinase family closely related to platelet-derived growth factor receptor (PDGFR). It is a transmembrane receptor and the cellular homolog of the HZ4-feline sarcoma virus transforming gene ...    Read more.

Read more CD117/c-kit related blogs.