Species: Mu
Applications: WB, IHC
Host: Goat Polyclonal
Species: Hu
Applications: WB, ICC/IF, IP
Host: Rabbit Polyclonal
Species: Hu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
DIXDC1 (DIX domain containing 1/Dixin) is a 683 amino acid protein. It positively regulates the Wnt signaling pathway by activating WNT3A via DVL2. It is expressed ubiquitously but has higher expression in skeletal and cardiac muscle. WNT3A signaling increases DIXDC1 protein levels by inhibiting its ubiquitination and subsequent degradation. DIXDC1 may play a role in breast cancer, breast carcinoma, endometrial cancer, epithelial neoplasia, schizophrenia, colon cancer, and neuroblastoma.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
85458 |
| Alternate Names |
- CCD1
- Coiled-coil protein DIX1
- Coiled-coil-DIX1
- DIX domain containing 1
- DIX domain-containing protein 1
- dixin
- KIAA1735coiled-coil-DIX1
|
Research Areas for Ccd1/DIXDC1
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction
![Western Blot Ccd1/DIXDC1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Ccd1_AF5599_Western_Blot_5776.jpg)
![Immunohistochemistry Ccd1/DIXDC1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Ccd1_AF5599_Immunohistochemistry_11453.jpg)
