Caspr2 Products

Description

Caspr2 encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons and associated with potassium channels. It may play a role in the local differentiation of the axon into distinct functional subdomains. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It may represent a positional candidate gene for the DFNB13 form of nonsyndromic deafness.

Bioinformatics

Product By Gene ID	26047
Alternate Names	AUTS15 Caspr2 CASPR2DKFZp781D1846 CDFE Cell recognition molecule Caspr2 CNTNAP2 contactin associated protein-like 2 contactin-associated protein 2 contactin-associated protein-like 2 homolog of Drosophila neurexin IV KIAA0868 NRXN4 NRXN4Caspr2 PTHSL1

Research Areas for Caspr2

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Neuroscience