Species: Hu
Applications: WB, Simple Western, IHC, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Bv, Ch, Rb
Applications: WB, IHC, IHC-P, IP (-), KD
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, ICC/IF, PLA, S-ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: PAGE
Description
Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIalpha, gamma, e and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2beta2 or an alphaalpha'beta2 structure. The a catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
Bioinformatics
Entrez |
Rat Mouse Human |
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
1457 |
Alternate Names |
- casein kinase 2, alpha 1 polypeptide
- casein kinase II alpha 1 subunit
- CK II alpha
- CK2 catalytic subunit alpha
- CK2A1casein kinase II subunit alpha
- CKII
- EC 2.7.11
- EC 2.7.11.1
- protein kinase CK2
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Bioinformatics Tool for Casein Kinase 2 alpha
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