CaM Kinase II alpha Products

Antibodies
CaM Kinase II alpha Antibody ...
CaM Kinase II alpha Antibody (6G9)
NB100-1983
Species: Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP, RIA
Host: Mouse Monoclonal
CaM Kinase II alpha [p Thr286 ...
CaM Kinase II alpha [p Thr286] Ant...
NB300-184
Species: Rt, Human, Mouse, Xenopus
Applications: WB
Host: Rabbit Polyclonal
CaM Kinase II alpha Antibody
CaM Kinase II alpha Antibody
NBP1-51945
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
Lysates
CaM Kinase II alpha Overexpre ...
CaM Kinase II alpha Overexpression...
H00000815-T01
Species: Hu
Applications: WB
CaM Kinase II alpha Overexpre ...
CaM Kinase II alpha Overexpression...
NBL1-08661
Applications: WB
Proteins
CaM Kinase II alpha Recombina ...
CaM Kinase II alpha Recombinant Pr...
H00000815-P01
Species: Hu
Applications: WB, ELISA, PA
CaM Kinase II alpha Partial R ...
CaM Kinase II alpha Partial Recomb...
H00000815-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
CaM Kinase II alpha RNAi
CaM Kinase II alpha RNAi
H00000815-R03
Species: Hu
Applications: RNAi, RNAi SP
CaM Kinase II alpha RNAi
CaM Kinase II alpha RNAi
H00000815-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

Calcium/calmodulin-dependent protein kinase II (CaMKII) is a widely distributed protein kinase that regulates numerous physiological functions. Inhibitors of CaMKII are useful tools for investigating the CaMKII functions (1). The synapse contains densely localized and interacting proteins that enable it to adapt to changing inputs. A Ca2+-sensitive protein complex involved in the regulation of AMPA receptor synaptic plasticity. The complex is comprised of MUPPI, a multi-PDZ domain-containing protein; SynGAP, a synaptic GTPase-activating protein; and the Ca2+/calmodulin-dependent kinase CaMKII. In synapses of hippocampal neurons, SynGAP and CaMKII are brought together by direct physical interaction with the PDZ domains of MUPP1, and in this complex, SynGAP is phosphorylated. Ca2+CaM binding to CaMKII dissociates it from the MUPP1 complex, and Ca2+ entering via the NMDAR drives the dephosphorylation of SynGAP (2).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Rat
Product By Gene ID 815
Alternate Names
  • EC 2.7.11.17
  • EC 2.7.11
  • CaMK-II subunit alpha
  • CaMK-II alpha subunit
  • CaM kinase II subunit alpha
  • CaM-kinase II alpha chain
  • calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
  • CaM kinase II alpha subunit
  • CaMKIINalpha
  • CAMKAcalcium/calmodulin-dependent protein kinase type II subunit alpha
  • KIAA0968calcium/calmodulin-dependent protein kinase type II alpha chain
  • calcium/calmodulin-dependent protein kinase II alpha-B subunit
  • calcium/calmodulin-dependent protein kinase II alpha

Research Areas for CaM Kinase II alpha

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Neurotransmission
Phospho-Specific
Protein Kinase
Signal Transduction
Tyrosine Kinases
Wnt Signaling Pathway

PTMs for CaM Kinase II alpha

Learn more about PTMs related to CaM Kinase II alpha.

Phosphorylation
Cleavage
Dephosphorylation
Acetylation
Methylation
Palmitoylation
Ubiquitination
Myristoylation

Bioinformatics Tool for CaM Kinase II alpha

Discover related pathways, diseases and genes to CaM Kinase II alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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