ARHGEF4 Products

Antibodies
Lysates
ARHGEF4 Overexpression Lysate ...
ARHGEF4 Overexpression Lysate
NBL1-07682
Species: Hu
Applications: WB
Proteins
Recombinant Human ARHGEF4 GST ...
Recombinant Human ARHGEF4 GST (N-T...
H00050649-Q02
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human ARHGEF4 GST ...
Recombinant Human ARHGEF4 GST (N-T...
H00050649-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
ARHGEF4 Recombinant Protein A ...
ARHGEF4 Recombinant Protein Antigen
NBP1-88857PEP
Species: Hu
Applications: AC

Description

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through Gucleotide exchange protein coupled receptors. Acts as guanine nucleotide exchange factor (GEF) for RhoA and RAC1 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. This protein is similar to rat collybistin protein. Alternative splicing of the gene generates two transcript variants which encode different isoforms.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 50649
Alternate Names
  • APC-stimulated guanine nucleotide exchange factor 1
  • GEF4
  • Asef1
  • ASEF1
  • Asef
  • KIAA1112
  • rho guanine nucleotide exchange factor 4
  • STM6
  • ASEFAPC-stimulated guanine nucleotide exchange factor
  • Rho guanine nucleotide exchange factor (GEF) 4

Research Areas for ARHGEF4

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Signal Transduction

Bioinformatics Tool for ARHGEF4

Discover related pathways, diseases and genes to ARHGEF4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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