ARHGEF4 Products

Antibodies
ARHGEF4 Antibody
ARHGEF4 Antibody
NB100-1316
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
ARHGEF4 Antibody
ARHGEF4 Antibody
NBP1-88857
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ARHGEF4 Overexpression Lysate ...
ARHGEF4 Overexpression Lysate (Nat...
NBL1-07682
Applications: WB
Proteins
ARHGEF4 Partial Recombinant P ...
ARHGEF4 Partial Recombinant Protein
H00050649-Q02
Species: Hu
Applications: WB, ELISA, PA
ARHGEF4 Partial Recombinant P ...
ARHGEF4 Partial Recombinant Protein
H00050649-Q01
Species: Hu
Applications: WB, ELISA, PA
ARHGEF4 Recombinant Protein A ...
ARHGEF4 Recombinant Protein Antigen
NBP1-88857PEP
Species: Hu
Applications: AC
RNAi
ARHGEF4 RNAi
ARHGEF4 RNAi
H00050649-R01
Species: Hu
Applications: RNAi, RNAi SP
ARHGEF4 RNAi
ARHGEF4 RNAi
H00050649-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through Gucleotide exchange protein coupled receptors. Acts as guanine nucleotide exchange factor (GEF) for RhoA and RAC1 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. This protein is similar to rat collybistin protein. Alternative splicing of the gene generates two transcript variants which encode different isoforms.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 50649
Alternate Names
  • APC-stimulated guanine nucleotide exchange factor 1
  • GEF4
  • Asef1
  • ASEF1
  • Asef
  • KIAA1112
  • rho guanine nucleotide exchange factor 4
  • STM6
  • ASEFAPC-stimulated guanine nucleotide exchange factor
  • Rho guanine nucleotide exchange factor (GEF) 4

Research Areas for ARHGEF4

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

Bioinformatics Tool for ARHGEF4

Discover related pathways, diseases and genes to ARHGEF4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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