APRIL/TNFSF13 Products

Antibodies
APRIL/TNFSF13 Antibody (April ...
APRIL/TNFSF13 Antibody (Aprily-8)
NBP1-97587
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Host: Mouse Monoclonal
APRIL/TNFSF13 Antibody [Uncon ...
APRIL/TNFSF13 Antibody [Unconjugated]
AF884
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
APRIL/TNFSF13 Antibody (67082 ...
APRIL/TNFSF13 Antibody (670820) [U...
MAB5860
Species: Hu
Applications: B/N
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human APRIL/TNFSF13 ELISA Kit ...
Human APRIL/TNFSF13 ELISA Kit (Col...
NBP1-82419
Species: Hu
Applications: ELISA
Lysates
APRIL/TNFSF13 Overexpression ...
APRIL/TNFSF13 Overexpression Lysate
NBL1-17165
Species: Hu
Applications: WB
APRIL/TNFSF13 Overexpression ...
APRIL/TNFSF13 Overexpression Lysate
NBL1-17164
Species: Hu
Applications: WB
Proteins
Recombinant Human APRIL/TNFSF ...
Recombinant Human APRIL/TNFSF13 (H...
5860-AP
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse APRIL/TNFSF ...
Recombinant Mouse APRIL/TNFSF13 Pr...
NBP2-35145
Species: Mu
Applications: Func, PAGE, Bioactivity
Recombinant Mouse APRIL/TNFSF ...
Recombinant Mouse APRIL/TNFSF13 Pr...
7907-AP
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

TNFSF13 is a proliferation-inducing ligand (APRIL), also designated TNFSF13, is a Type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. APRIL is expressed in high levels in transformed cell lines and in human colon, thyroid, and lymphoid tumor tissues. APRIL is critically involved in the regulation of infections, inflammation, autoimmune diseases, and tissue homeostasis. APRIL is implicated in the regulation of tumor cell growth. The C-terminal extracellular domain has b jelly roll topography and is important in ligand trimerization. The binding of the ligand to its respective receptor induces oligomerization, initiating downstream signaling events. Intrinsic to oligomerization is the formation of the receptor binding site at the junction between neighboring subunits, creating a multivalent ligand.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 8741
Alternate Names
  • CD256 antigen
  • TNF- and APOL-related leukocyte expressed ligand 2
  • tumor necrosis factor-related death ligand-1
  • ZTNF2
  • tumor necrosis factor-like protein ZTNF2
  • TRDL-1
  • tumor necrosis factor ligand superfamily member 13
  • TALL2
  • TALL-2
  • A proliferation-inducing ligand
  • CD256
  • APRILFLJ57090
  • TNF-related death ligand 1
  • tumor necrosis factor (ligand) superfamily, member 13

Research Areas for APRIL/TNFSF13

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cell Cycle and Replication
Cytokine Research
Immunology

PTMs for APRIL/TNFSF13

Learn more about PTMs related to APRIL/TNFSF13.

Phosphorylation
Cleavage
Dephosphorylation

Bioinformatics Tool for APRIL/TNFSF13

Discover related pathways, diseases and genes to APRIL/TNFSF13. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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