4EBP1 Products

Antibodies
4EBP1 Antibody
4EBP1 Antibody
NB200-157
Species: Hu, Mu, Rt, Po, Primate, Rabbit, Chinese Hamster, Squirrel, Rhesus Macaque
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
4EBP1 Antibody [Unconjugated] ...
4EBP1 Antibody [Unconjugated]
AF3227
Species: Hu, Mu
Applications: WB, Simple Western
Host: Goat Polyclonal
4EBP1 Antibody
4EBP1 Antibody
NBP1-89368
Species: Hu, Mu, Rt, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
4EBP1 Overexpression Lysate ( ...
4EBP1 Overexpression Lysate (Native)
NBL1-10206
Applications: WB
Proteins
4EBP1 Recombinant Protein
4EBP1 Recombinant Protein
NBP1-30218
Species: Hu
Applications: PAGE
4EBP1 Recombinant Protein Ant ...
4EBP1 Recombinant Protein Antigen
NBP1-89368PEP
Species: Hu
Applications: AC
4EBP1 Peptide
4EBP1 Peptide
NBP1-76621PEP
Species: Hu
Applications: AC
RNAi
4EBP1 RNAi
4EBP1 RNAi
H00001978-R01
Species: Hu

Description

4E-BP1 (eIF4E-binding protein) also known as PHAS, is a 10-12 kDa acidic protein that compete with eIF4G for binding of eiF4E to the mRNA 5' cap structure (1). Binding of the 4E-BPs to eIF4E is reversible and is dependent on the phosphorylation status of 4E-BP. Non-phosphorylated 4E-BP1 will bind strongly to eiF4E while, the phosphorylated form will no (2)t. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating 4E-BP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the 4EBP1-eIF4E interaction (3-4)

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 1978
Alternate Names
  • eIF4E-binding protein 1
  • eukaryotic translation initiation factor 4E-binding protein 1
  • Phosphorylated heat- and acid-stable protein regulated by insulin 1
  • PHAS-IMGC4316
  • eukaryotic translation initiation factor 4E binding protein 1,4EBP1,4E-BP1BP-1

Research Areas for 4EBP1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Core ESC-Like Genes
DNA Repair
DNA replication, Transcription, Translation and Splicing
Lipid and Metabolism
mTOR Pathway
Phospho-Specific
Stem Cell Markers

Bioinformatics Tool for 4EBP1

Discover related pathways, diseases and genes to 4EBP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.