Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Rt
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq]
Bioinformatics
| Product By Gene ID |
9915 |
| Alternate Names |
- ARNT protein 2
- aryl-hydrocarbon receptor nuclear translocator 2
- bHLHe1BHLHE1
- Class E basic helix-loop-helix protein 1
- KIAA0307aryl hydrocarbon receptor nuclear translocator 2
|
