BRCA2 antibody

Breast Cancer and RAD51L1 Antibodies

In the United States, breast cancer is one of the most common cancers and the second leading cause of cancer related deaths in women. According to the American Cancer Society's most recent estimates for breast cancer in the United States, there are about 200,000 new cases of invasive breast cancer, 60,000 new cases of carcinoma in situ (CIS),  and approximately 40,000 deaths from breast cancer this year.

Determining DMC1's role in Homologus Recombination

The DMC1 gene encodes a 36.7 kDa nuclear protein involved in meiotic homologous recombination. This recombinase is functionally related to the yeast RAD51 and E. coli RecA genes. In contrast to RAD51, which functions in both mitotic and meiotic recombination, DMC1 works specifically in meiotic recombination. Despite this difference, the RAD51 and DMC1 recombinase are structurally similar but not identical in nature.

Rad51 Antibody Reveals a Canine Model for Human Breast Cancer

Our antibody catalog includes an extensive range of Rad51 antibody reagents. Encoded by the RAD51 gene, the Rad51 protein plays a vital role in DNA repair, interacting with several other proteins, including BRCA1 and BRCA2, to effect homologous recombination at double-strand breaks.

Industrial Chemicals, Tumour Suppressor Genes and the Need for More Research

Human cancer research is the largest research area in our antibody database, with new oncogenes and cell lines being added all the time.

Fanconi Antibodies and Cancer Research