Novus Biologicals Releases Two New Sorting Nexin Family Antibodies

Novus Biologicals just released two new SNX27 antibodies (NBP1-45282 and NBP1-45283) for use in Western blot and immunocytochemistry/immunofluorescence. These rabbit polyclonal antibodies are affinity purified and their immunogens are synthetic peptides made to internal portions of the human SNX27 protein (Swiss-Prot# Q96L92).

SNX27 is a member of the sorting nexin family of proteins that is involved in endocytic trafficking. In T lymphocytes, Sorting nexin-27 participates in the endocytic recycling pathway. It has also been shown that the single PDZ domain of SNX-27 binds directly to the PDZ binding motif of Kir3 channels leading to their downregulation.

Novus' new anti-SNX27 antibodies were detected by immunocytochemistry in HeLa cells (green) and the nuclei were counterstained using Hoechst 33258 (blue).  By Western blot, the SNX27 antibodies produced bands at ~65 kDa in the 293T cell line tagged with SNX27 protein.  NBP1-45283 was also validated for use in Western blot by testing in mouse brain extracts.

These SNX27 antibodies are available in two sizes (0.1mL and 25uL), and can also be requested in bulk quantities.  Novus also offers other Sorting Nexin Family antibodies which can be browsed here and narrowed down by target, species, etc. using the filters on the left.


For more information on these new SNX27 antibodies or to inquire about product collaborations, please contact the Novus Product Development Team by calling 303-730-1950 or via e-mail at

Release Date: 
Thursday, September 2, 2010 - 06:00