Integrin beta 1/CD29 Products

Description

Integrin beta 1, also known as CD29, is a 130 kDa transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits (including alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, and alpha 6, also known as CD49a, CD49b, CD49c, CD49d, CD49e, and CD49f, respectively) to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis, and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. These heterodimeric receptors bridge the cytoplasmic actin cytoskeleton with proteins present in the extracellular matrix and/or on adjacent cells. The clustering of integrins on a cell surface leads to the formation of focal contacts. Interactions between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression.

Bioinformatics

Entrez	3688 Human 16412 Mouse
Product By Gene ID	3688
Alternate Names	CD29 antigen CD29 Fibronectin receptor subunit beta FNRBVLAB GPIIA Integrin beta 1 integrin beta-1 integrin VLA-4 beta subunit integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includesMDF2, MSK12) ITGB1 MDF2 MSK12 very late activation protein, beta polypeptide VLA-4 subunit beta VLA-BETA

Research Areas for Integrin beta 1/CD29

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Biology
Cellular Markers
Cytokine Research
Immunology
Mesenchymal Stem Cell Markers
Neuronal Cell Markers
Phospho-Specific
Signal Transduction
Stem Cell Markers

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Integrin Beta 1/CD29 - a cell adhesion and cell signaling protein with diverse functions Integrins are a large family of trasmembrane proteins involved in cell adhesion and form a link between the intracellular cyskeletal proteins and extracellular matrix proteins. Integrins exist as heterodimers consisting of alpha and beta subunits. ...    Read more.

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