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Vitronectin also called serum spreading factor or complement S-protein, is a member of the pexin family (1). Found in serum and in tissues, Vitronectin exist in two forms; as a single chain (75kDa) and as a clipped form composed of two chains (65kDa and 10kDa). Vitronectin promotes cell adhesion, spreading and migration through specific interactions with cellular integrins, and inhibits cytolysis by the complement C5b-9 complex (2-4). Vitronectin also interacts with several critical proteins that regulate thrombosis and fibrinolysis. Vitronectin is phosphorylated by PKA and CKII (5).
![Immunohistochemistry Vitronectin Antibody (347317) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/Vitronectin_MAB38751_Immunohistochemistry_7011.jpg)
![Western Blot Vitronectin Antibody (342603) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/Vitronectin_MAB2349_Western_Blot_20043.jpg)
![Sandwich ELISA Vitronectin Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Vitronectin-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79457-img0001.jpg)
![Immunohistochemistry Vitronectin Antibody (342603) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/Vitronectin_MAB2349_Immunohistochemistry_7361.jpg)
![Simple Western Vitronectin Antibody (342603) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/16254.jpg)
![Western Blot Vitronectin Antibody (342603) [Unconjugated]](http://images.novusbio.com/fullsize/mab2349_human-vitronectin-mab-clone-342603-western-blot-12122025825249.jpg)
