Transferrin Products

Description

Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.

Bioinformatics

Entrez	22041 Mouse 24825 Rat 7018 Human
Uniprot	AAH59367 Human NM_001063 Human NP_001054.1 Human P02787 Human
Product By Gene ID	7018
Alternate Names	Beta-1 metal-binding globulin DKFZp781D0156 EC 3.4.21 PRO1557 PRO2086 serotransferrin siderophilin Siderophilin Transferrin transferrin

Research Areas for Transferrin

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Apoptosis
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Cellular Markers
Golgi Apparatus Markers
Stem Cell Markers

Related Transferrin Blog Posts

Check out the latest blog posts on Transferrin.

Transferrin: "Ironing" out the Details of Cellular Anemia Transferrin is a protein found in the blood plasma, a glycoprotein that is specific for controlling free iron in the bodies' biological fluids. Transferrin has two binding sites that are specific for very tight and reversible iron binding. The binding...    Read more.

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