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Thrombomodulin/BDCA-3 Products

Antibodies
Thrombomodulin/BDCA-3 Antibod ...
Thrombomodulin/BDCA-3 Antibody [Un...
AF3894
NL003) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry Thrombomodulin/BDCA-3 Antibody [Unconjugated]
VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell surface on endothelial cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank"> Immunohistochemistry Thrombomodulin/BDCA-3 Antibody [Unconjugated]
Species: Mu
Applications: WB, Flow, IHC, IP, CyTOF-ready, ICC/IF
Host: Goat Polyclonal
Thrombomodulin/BDCA-3 Antibod ...
Thrombomodulin/BDCA-3 Antibody (46...
MAB3894
NL013) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry Thrombomodulin/BDCA-3 Antibody (461714)
CTS017) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry Thrombomodulin/BDCA-3 Antibody (461714)
MAB0061, open histogram), followed by Phycoerythrin-conjugated Anti-Rat IgG F(ab')2Secondary Antibody (Catalog # F0105B)." class="big_lightbox" target="_blank"> Flow Cytometry Thrombomodulin/BDCA-3 Antibody (461714)
Species: Mu
Applications: WB, Flow, IHC, CyTOF-ready, ICC/IF
Host: Rat Monoclonal
Thrombomodulin/BDCA-3 Antibod ...
Thrombomodulin/BDCA-3 Antibody (50...
MAB3947
FAB4869A) and either (A) Mouse Anti-Human Thrombomodulin/BDCA-3 Monoclonal Antibody (Catalog # MAB3947) or (B) Mouse IgG1Isotype Control (Catalog # MAB002) followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B). View our protocol for Staining Membrane-associated Proteins." class="big_lightbox" target="_blank"> Flow Cytometry Thrombomodulin/BDCA-3 Antibody (501733) [Unconjugated]
CTS002) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry Thrombomodulin/BDCA-3 Antibody (501733) [Unconjugated]
3947-PA) was serially diluted and captured by Mouse Anti-Human Thrombomodulin/BDCA‑3 Monoclonal Antibody (Catalog # MAB3947) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human Thrombomodulin/BDCA‑3 Monoclonal Antibody (Catalog # MAB39471) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank"> ELISA Thrombomodulin/BDCA-3 Antibody (501733) [Unconjugated]
Species: Hu
Applications: Flow, IHC, CyTOF-ready, ELISA(Cap)
Host: Mouse Monoclonal
ELISA Kits
Human Thrombomodulin/BDCA-3 Q ...
Human Thrombomodulin/BDCA-3 Quanti...
DTHBD0
Species: Hu
Applications: ELISA
Human Thrombomodulin/BDCA-3 D ...
Human Thrombomodulin/BDCA-3 DuoSet...
DY3947
Species: Hu
Applications: ELISA
Mouse Thrombomodulin/BDCA-3 Q ...
Mouse Thrombomodulin/BDCA-3 Quanti...
MTHBD0
Species: Mu
Applications: ELISA
Proteins
Recombinant Human Thrombomodu ...
Recombinant Human Thrombomodulin/B...
3947-PA
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Recombinant Mouse Thrombomodu ...
Recombinant Mouse Thrombomodulin/B...
3894-PA
Species: Mu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Thrombomodulin/BDCA-3 Recombi ...
Thrombomodulin/BDCA-3 Recombinant ...
NBP1-88133PEP
Species: Hu
Applications: AC

Description

CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 7056
Alternate Names
  • BDCA3
  • CD141 antigen
  • CD141
  • fetomodulin
  • thrombomodulin
  • TM

Related Thrombomodulin/BDCA-3 Blog Posts

Check out the latest blog posts on Thrombomodulin/BDCA-3.
Thrombomodulin - A multifunctional protein with roles in inflammation and coagulation
Thrombomodulin, also known as BDCA-3, is a glycosylated transmembrane protein present on the surface of vascular endothelial cells. Thrombomodulin is a high-affinity receptor for thrombin, a key protein in the coagulation cascade. Formation of the...    Read more.
Read more Thrombomodulin/BDCA-3 related blogs.