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Siglec-3/CD33 Products

Antibodies
Siglec-3/CD33 Antibody (44M12 ...
Siglec-3/CD33 Antibody (44M12D3) -...
NBP2-22377
Western Blot Siglec-3/CD33 Antibody (44M12D3) - BSA Free
Immunohistochemistry-Paraffin Siglec-3/CD33 Antibody (44M12D3) - BSA Free
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 NBP2-22377AF350
Alexa Fluor 405 NBP2-22377AF405
Alexa Fluor 488 NBP2-22377AF488
Alexa Fluor 532 NBP2-22377AF532
Alexa Fluor 594 NBP2-22377AF594
Alexa Fluor 647 NBP2-22377AF647
Alexa Fluor 700 NBP2-22377AF700
Alexa Fluor 750 NBP2-22377AF750
Alexa Fluor Plus 405 NBP2-22377AFP405
Alexa Fluor Plus 488 NBP2-22377AFP488
Alexa Fluor Plus 555 NBP2-22377AFP555
Alexa Fluor Plus 594 NBP2-22377AFP594
Alexa Fluor Plus 647 NBP2-22377AFP647
Alexa Fluor Plus 680 NBP2-22377AFP680
Allophycocyanin NBP2-22377APC
Biotin NBP2-22377B
CoraFluor 1 NBP2-22377CL1
DyLight 350 NBP2-22377UV
DyLight 405 NBP2-22377V
DyLight 488 NBP2-22377G
DyLight 550 NBP2-22377R
DyLight 594 NBP2-22377DL594
DyLight 650 NBP2-22377C
DyLight 680 NBP2-22377FR
DyLight 755 NBP2-22377IR
FITC NBP2-22377F
HRP NBP2-22377H
Janelia Fluor 525 NBP2-22377JF525
Janelia Fluor 549 NBP2-22377JF549
Janelia Fluor 646 NBP2-22377JF646
Janelia Fluor 669 NBP2-22377JF669
PE NBP2-22377PE
PerCP NBP2-22377PCP
mFluor Violet 450 SE NBP2-22377MFV450
mFluor Violet 500 SE NBP2-22377MFV500
mFluor Violet 610 SE NBP2-22377MFV610
Formulation Catalog # Availability Price  
BSA Free NBP2-22377SS
Azide and BSA Free NBP2-80948
Siglec-3/CD33 Antibody (99681 ...
Siglec-3/CD33 Antibody (996810) [U...
MAB11371
DR647MS) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the membrane. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence Siglec-3/CD33 Antibody (996810) [Unconjugated]
DR647MS) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the membrane. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence Siglec-3/CD33 Antibody (996810) [Unconjugated]
DR647MS) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the membrane. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence Siglec-3/CD33 Antibody (996810) [Unconjugated]
DR647MS) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the membrane. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence Siglec-3/CD33 Antibody (996810) [Unconjugated]
VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to lymphocytes. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank"> Immunohistochemistry Siglec-3/CD33 Antibody (996810) [Unconjugated]
HAF018). A specific band was detected for Siglec-3/CD33 at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot Siglec-3/CD33 Antibody (996810) [Unconjugated]
NL007) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry Siglec-3/CD33 Antibody (996810) [Unconjugated]
Species: Hu
Applications: WB, IHC, COMET, ICC/IF
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 FAB11371U-100UG
Alexa Fluor 405 FAB11371V-100UG
Alexa Fluor 488 FAB11371G-100UG
Alexa Fluor 532 FAB11371X-100UG
Alexa Fluor 594 FAB11371T-100UG
Alexa Fluor 647 FAB11371R-100UG
Alexa Fluor 700 FAB11371N-100UG
Alexa Fluor 750 FAB11371S-100UG
Alexa Fluor Plus 405 FAB11371AFP405-100UG
Alexa Fluor Plus 488 FAB11371AFP488-100UG
Alexa Fluor Plus 555 FAB11371AFP555-100UG
Alexa Fluor Plus 594 FAB11371AFP594-100UG
Alexa Fluor Plus 647 FAB11371AFP647-100UG
Alexa Fluor Plus 680 FAB11371AFP680-100UG
Allophycocyanin FAB11371A
Biotin FAB11371B
CoraFluor 1 FAB11371CL1
DyLight 350 FAB11371D
DyLight 405 FAB11371E
DyLight 488 FAB11371K
DyLight 550 FAB11371L
DyLight 594 FAB11371M
DyLight 650 FAB11371W
DyLight 680 FAB11371Y
DyLight 755 FAB11371Z
FITC FAB11371F
HRP FAB11371H
Janelia Fluor 525 FAB11371JF525
Janelia Fluor 549 FAB11371I
Janelia Fluor 646 FAB11371J
Janelia Fluor 669 FAB11371JF669
PE FAB11371P
PerCP FAB11371C
mFluor Violet 450 SE FAB11371MFV450
mFluor Violet 500 SE FAB11371MFV500
mFluor Violet 610 SE FAB11371MFV610
Formulation Catalog # Availability Price  
Carrier Free MAB11371-100
Carrier Free MAB11371-SP
Siglec-3/CD33 Antibody (6C5/2 ...
Siglec-3/CD33 Antibody (6C5/2) [Un...
MAB1137
MAB002, open histogram) followed by anti-Mouse IgG PE-conjugated secondary antibody (Catalog # F0102B). View our protocol for Staining Membrane-associated Proteins." class="big_lightbox" target="_blank"> Flow Cytometry Siglec-3/CD33 Antibody (6C5/2) [Unconjugated]
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 FAB1137U-100UG
Alexa Fluor 405 FAB1137V-100UG
Alexa Fluor 488 FAB1137G-100UG
Alexa Fluor 532 FAB1137X
Alexa Fluor 594 FAB1137T-100UG
Alexa Fluor 647 FAB1137R-100UG
Alexa Fluor 700 FAB1137N-100UG
Alexa Fluor 750 FAB1137S-100UG
Alexa Fluor Plus 405 FAB1137AFP405-100UG
Alexa Fluor Plus 488 FAB1137AFP488-100UG
Alexa Fluor Plus 555 FAB1137AFP555-100UG
Alexa Fluor Plus 594 FAB1137AFP594-100UG
Alexa Fluor Plus 647 FAB1137AFP647-100UG
Alexa Fluor Plus 680 FAB1137AFP680-100UG
Allophycocyanin FAB1137A-100
Allophycocyanin FAB1137A-025
Allophycocyanin/Cy7 FAB1137APCCY7
Biotin FAB1137B
CoraFluor 1 FAB1137CL1
DyLight 350 FAB1137D
DyLight 405 FAB1137E
DyLight 488 FAB1137K
DyLight 550 FAB1137L
DyLight 594 FAB1137M
DyLight 650 FAB1137W
DyLight 680 FAB1137Y
DyLight 755 FAB1137Z
HRP FAB1137H
Janelia Fluor 525 FAB1137JF525
Janelia Fluor 549 FAB1137I
Janelia Fluor 646 FAB1137J
Janelia Fluor 669 FAB1137JF669
PE/Atto594 FAB1137PEATT594
PE/Cy5.5 FAB1137PECY55
PE/Cy7 FAB1137PECY7
PerCP FAB1137C
Phycoerythrin FAB1137P-100
Phycoerythrin FAB1137P-025
mFluor Violet 450 SE FAB1137MFV450
mFluor Violet 500 SE FAB1137MFV500
mFluor Violet 610 SE FAB1137MFV610
Formulation Catalog # Availability Price  
Carrier Free FAB1137P-025
Carrier Free FAB1137P-100
Carrier Free FAB1137A-025
Carrier Free FAB1137A-100
Carrier Free MAB1137-SP
Carrier Free MAB1137-100
Carrier Free MAB1137-500
Carrier Free FAB1137V-100UG
Carrier Free FAB1137U-100UG
Carrier Free FAB1137T-100UG
Carrier Free FAB1137S-100UG
Carrier Free FAB1137R-100UG
Carrier Free FAB1137N-100UG
Carrier Free FAB1137G-100UG
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We have 58 Siglec-3/CD33 Antibodies
ELISA Kits
Human Siglec-3/CD33 ELISA Kit ...
Human Siglec-3/CD33 ELISA Kit (Col...
NBP3-49937
ELISA Human Siglec-3/CD33 ELISA Kit (Colorimetric)
ELISA Human Siglec-3/CD33 ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
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We have 1 Siglec-3/CD33 ELISA Kit
Lysates
Siglec-3/CD33 Overexpression ...
Siglec-3/CD33 Overexpression Lysate
NBP2-04204
Western Blot Siglec-3/CD33 Overexpression Lysate
Species: Hu
Applications: WB
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We have 1 Siglec-3/CD33 Lysate
Proteins
Recombinant Human Siglec-3/CD ...
Recombinant Human Siglec-3/CD33 Fc...
1137-SL
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Carrier Free 1137-SL-050
Recombinant Human Siglec-3/CD ...
Recombinant Human Siglec-3/CD33 Fc...
AVI10467
AVI10467) supports the adhesion of human red blood cells. The ED50 for this effect is 0.2-1.4 μg/mL." class="big_lightbox" target="_blank"> Binding Activity Siglec-3/CD33 [Biotin]
SDS-Page Siglec-3/CD33 [Biotin]
Species: Hu
Applications: Bioactivity
Conjugate Catalog # Availability Size Price
Biotin AVI10467-050
Formulation Catalog # Availability Price  
Carrier Free AVI10467-050
Recombinant Human Siglec-3/CD ...
Recombinant Human Siglec-3/CD33 Hi...
AVI1137
MAB1137) is immobilized at 0.5 µg/mL, 100 µL/well, Biotinylated Recombinant Human Siglec-3/CD33 His-tag Avi-tag (Catalog # AVI1137) binds with an ED50 of 60-360 pg/mL." class="big_lightbox" target="_blank"> Binding Activity Siglec-3/CD33 [Biotin]
2 μg/lane of Biotinylated Recombinant Human Siglec-3/CD33 His-tag Avi-tag (Catalog # AVI1137) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 45-52 kDa.
" class="big_lightbox" target="_blank"> SDS-Page Siglec-3/CD33 [Biotin]
Species: Hu
Applications: Bioactivity
Conjugate Catalog # Availability Size Price
Biotin AVI1137-050
Formulation Catalog # Availability Price  
Carrier Free AVI1137-050
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We have 12 Siglec-3/CD33 Proteins

Description

CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages, although it is absent on granulocytes. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function. (1-4)

Bioinformatics

Entrez
945
Human
Uniprot
AAA51948
Human
AAH28152
Human
AAH28152.1
Human
NM_001772
Human
NP_001763
Human
P20138
Human
Product By Gene ID 945
Alternate Names
  • CD33 antigen (gp67)
  • CD33 antigen
  • CD33 molecule
  • FLJ00391
  • myeloid cell surface antigen CD33
  • p67
  • sialic acid binding Ig-like lectin 3
  • Sialic acid-binding Ig-like lectin 3
  • SIGLEC-3
  • Siglec-3
  • SIGLEC3gp67

Research Areas for Siglec-3/CD33

Find related products by research area and learn more about each of the different research areas below.

Immunology

Related Siglec-3/CD33 Blog Posts

Check out the latest blog posts on Siglec-3/CD33.
Harnessing Natural Killer Cell Activity for Anti-Tumor Immunotherapy
By Victoria Osinski, PhDWhat’s “Natural” About Natural Killer (NK) Cells?For immunologists, the term cytotoxicity often conjures up images of an army of antigen specific CD8+ T cells deploying to ...    Read more.
Read more Siglec-3/CD33 related blogs.