USH1C Antibody

Product Discontinued

USH1C Antibody Summary

• Immunogen: This antibody is specific for the Middle Region, a.a. 276-393, of the target protein (NM_023649).
• Specificity: This product is specific for Human USH1c.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: USH1C
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot
• Application Notes: This antibody is useful in ELISA and Immunohistochemistry-Paraffin. Western Blot was reported in scientific literature.

Reactivity Notes

Human and Mouse.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for USH1C Antibody

• AIE75
• AIE-75
• Antigen NY-CO-38/NY-CO-37
• Autoimmune enteropathy-related antigen AIE-75
• deafness, autosomal recessive 18
• DFNB18
• harmonin
• NY-CO-37
• NY-CO-38
• PDZ-45
• PDZ73
• PDZ-73
• PDZ-73/NY-CO-38
• Protein PDZ-73
• Renal carcinoma antigen NY-REN-3
• ush1cpst
• Usher syndrome 1C (autosomal recessive, severe)
• Usher syndrome type-1C protein

Background

USH1C may be involved in protein-protein interaction. Defects in USH1C are the cause of Usher syndrome type 1c. It is an autosomal recessive sensory defect involving congenital profound sensorineural deafness, vestibular dysfunction, and blindness due to progressive retinitis pigmentosa. Defects in USH1C are also the cause of nonsyndromic recessive deafness.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for USH1C Antibody (20900002)(3)

Publications using 20900002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.
• Lentz JJ, Jodelka FM, Hinrich AJ et al. Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness. Nat Med 2013-02-04 [PMID: 23380860] (WB, Mouse)

Bioinformatics

• Gene Symbol: USH1C