Staphylococcus Aureus Antibody - BSA Free

• Reactivity: Ba
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 4.0 mg/ml

Staphylococcus Aureus Antibody - BSA Free Summary

• Immunogen: Staphylococcus aureus
• Specificity: Reacts with soluble and structural antigens of the whole bacterium. It is not absorbed for related microorganisms.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Frozen
• Application Notes: Use in Immunohistochemistry-Frozen reported in scientific literature (PMID: 31665625).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 4.0 mg/ml
• Purity: IgG purified

Alternate Names for Staphylococcus Aureus Antibody - BSA Free

• S. aureus

Background

Staphylococcal enterotoxins represent a group of proteins, which are secreted by Staphylococcus aureus and cause the intoxication staphylococcal food poisoning syndrome. The illness characterized by high fever, hypo tension, diarrhea, shock, and in some cases death. Their molecular masses range between 27 and 30 kDa. At present, seven enterotoxins are known, namely A, B, C1, C2, C3, D and E. Their amino acid sequences have been determined and it was shown that all are single chain polypeptides containing one disulfide bond formed by two half cystines located in the middle of the polypeptide chain, which form the so called cysteine loop. Enterotoxins are extremely potent activator of T cells, stimulating the production and secretion of various cytokines which mediate many of the toxic effects of these substances. Enterotoxins are Superantigens, inducing polyclonal T cell activation by binding to the TCR and to the alpha chain of the MHC II molecule simultaneously.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Staphylococcus Aureus Antibody (NB100-64499)(3)

Publications using NB100-64499

• Focken J, Scheurer J, Jäger A et al. Neutrophil extracellular traps enhance S. aureus skin colonization by oxidative stress induction and downregulation of epidermal barrier genes Cell reports 2023-09-19 [PMID: 37733587]
• Wang J, Blalock S, Levitan G et al. Biological mechanisms of infection resistance in tissue engineered blood vessels compared to synthetic expanded polytetrafluorethylene grafts JVS-Vascular Science 2023-07-14 [PMID: 37662589] (IHC, Bacteria)
• Schulz A, Jiang L, de Vor L et al. Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization Cell Rep 2019-10-29 [PMID: 31665625] (IHC-Fr)