Smallpox B5R Antibody

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Western Blot: Smallpox B5R Antibody [NB100-56453] - analysis of B5R in (A) recombinant fusion protein containing amino acids 200-214 and (B) fusion partner without these amino acids, using this antibody. 0.1 ug/ml.

Product Details

Summary
Reactivity V-ViSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Smallpox B5R Antibody Summary

Immunogen
Amino acids 200-214 (GSDVDKKDTHGNTPF) of the B5R protein were used as the immunogen.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
B7R
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.1-1 ug/ml

Reactivity Notes

Reacts with Variola virus.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.2% gelatin
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified

Alternate Names for Smallpox B5R Antibody

  • B5R protein
  • B6R
  • B7R protein
  • B7R
  • EEV membrane glycoprotein
  • Glycoprotein
  • H7R protein
  • H7R
  • ORF5R
  • VARVgp175

Background

Vaccinia virus, a member of Poxviridae family, is a dsDNA enveloped virus. It consists of 4 types of virion stages among which extracellular enveloped virus (EEV) is critical for cell-to-cell and long range viral infection. B5R is an EEV-specific Type I membrane glycoprotein essential for EEV formation. It consists of a large ectodomain containing regions similar to SCR domains of complement regulatory proteins followed by a transmembrane region and a cytoplasmic tail. B5R is essential for efficient wrapping of IMV, actin tail formation, normal plaque size, virus virulence, incorporation of the protein into EEV and for EEV formation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional Smallpox B5R Products

Array NB100-56453

Bioinformatics Tool for Smallpox B5R Antibody (NB100-56453)

Discover related pathways, diseases and genes to Smallpox B5R Antibody (NB100-56453). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Bioinformatics

Gene Symbol B7R