The antibody was developed by immunizing rabbits with a synthetic peptide corresponding to amino acids 288-303 (AVDCALDPLSETKCTL) from the S (Spike glycoprotein)(Spike protein 1) for the Human SARS coronavirus (Genbank accession no. YP_009724390)
The was tested on a cell line transfected with a partial-length cDNA coding for the N-terminal portion of SARS Spike protein with a predicted molecular weight of 68 kDa.
Protein G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Expected species cross reactivity based on immunogen sequence homology: COVID-19 (69%)
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS containing 0.2% gelatin
0.05% Sodium Azide
Protein G purified
Alternate Names for Sars Spike Protein Antibody
Human coronavirus spike glycoprotein
SARS coronavirus S protein
SARS coronavirus Spike Protein
SARS CoV S glycoprotein
SARS CoV Spike protein
SARS-CoV S protein
Severe acute respiratory syndrome spike glycoprotein
Severe acute respiratory syndrome virus spike glycoprotein
It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosilated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Publications for Sars Spike Protein Antibody (NB100-56048)(3)
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PRODUCT AVAILABILITY: Update Regarding the Evolving COVID-19 Situation
Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.