SARS Nucleocapsid Protein Antibody Summary
The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 20-34 of putative SARS nucleocapsid (Genbank accession no. NP_828858).
The was tested on a cell line transfected with full-length SARS Nucleocapsid cDNA with a predicted molecular weight of 46 kDa.
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Western Blot 1:100-1:2000
- ELISA 1:100-1:2000
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Whole antisera with PBS and 0.2% Gelatin
0.05% Sodium Azide
Alternate Names for SARS Nucleocapsid Protein Antibody
- N protein
- N structural protein
- Nucleocapsid protein
- SARS coronavirus N protein
- SARS coronavirus nucleocapsid protein
- SARS CoV N protein
- SARS CoV nucleocapsid protein
- SARS CoV
- SARS N protein
- SARSCoV N protein
- SARSCoV nucleocapsid protein
- Severe acute respiratory syndrome
It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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