SARS Nucleocapsid Protein Antibody Pack

Product Discontinued

SARS Nucleocapsid Protein Antibody Pack Summary

• Immunogen: The following antibodies are included in this SARS-Nucleocapsid antibody bundle: Format: Mouse ascites; Application: western blot; Immunogen: amino acids 354-370
  Format: Purified Mouse IgG2b monoclonal antibody; Application: western blot, IF/ICC; Immunogen: full length recombinant protein
  Format: Rabbit sera; Application: western blot, ELISA; Immunogen: amino acids 354-370
  Format: Purified Rabbit IgG polyclonal antibody; Application: western blot, IF/ICC; Immunogen: amino acids 399-411
  Format: Purified Rabbit IgG polyclonal antibody; Application: western blot, ELISA; Immunogen: amino acids 20-34
  Format: Rabbit sera; Application: western blot, ELISA; Immunogen: amino acids 84-99
• Gene: N

Applications/Dilutions

• Dilutions:
  • Peptide ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Alternate Names for SARS Nucleocapsid Protein Antibody Pack

• N protein
• N structural protein
• N
• NC
• Nucleocapsid protein
• Nucleoprotein
• Protein N
• SARS coronavirus N protein
• SARS coronavirus nucleocapsid protein
• SARS CoV N protein
• SARS CoV nucleocapsid protein
• SARS CoV
• SARS N protein
• SARS Nucleoprotein
• SARSCoV N protein
• SARSCoV nucleocapsid protein
• SARSCoV
• Severe acute respiratory syndrome

Background

It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Packs are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: N