Respiratory Syncytial Virus Glycoprotein F Antibody (11-3-A3)

Images

 
Western Blot: Respiratory Syncytial Virus Glycoprotein F Antibody (RSV 11-3-A3) [NBP2-50392] - The antigen in all lanes was gradient purified RSN-A2 virus (subgroup A). Panel A: Antigen analysed by electrophoresis using ...read more

Product Details

Summary
Reactivity ViSpecies Glossary
Applications WB, ELISA, ICC/IF
Clone
11-3-A3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Respiratory Syncytial Virus Glycoprotein F Antibody (11-3-A3) Summary

Immunogen
Gradient-purified RSF-44 virus (subgroup A) UV inactivated for 20 minutes at 20C
Specificity
This antibody has a high neutralising activity; 90% plaque neutralization titre of 103 (Gimenez et al., 1996). This property makes it potentially useful for the preparation of reagents for prevention and/or for therapeutic use in managing RS virus infections (for example, vaccines or new-generation man-made antibodies).This antibody reacts with the fusion protein F (also named VP70 or F0 protein) and specifically to a subunit of the F protein, F1 (also named 48kDa). The antibody reacts with the RS virus F1 protein from both subgroups A and B of the virus.New-generation man-made antibodies, based on the 11-3-A3 antibody, could complement the effectiveness of polivizumab (Synagis), which is used to prevent but not treat established RS virus infections (Nature Biotechnology, 2013: 31, 952).Significantly, there was no evidence of antibody dependant enhancement of RS virus infection in vitro for the 11-3-A3 antibody. The enhancing activity was found for other antibodies to the F protein (Gimenez et al 1996).
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100 - 1:2000
  • ELISA 1:100 - 1:2000
  • Immunocytochemistry/Immunofluorescence 1:10 - 1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Notes

Positive control(s): Immunoblot: (see Figure) Indirect immunofluorescence: staining of RSA-2 infected BSC-1 cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Respiratory Syncytial Virus Glycoprotein F Antibody (NBP2-50392) (0)

There are no publications for Respiratory Syncytial Virus Glycoprotein F Antibody (NBP2-50392).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Respiratory Syncytial Virus Glycoprotein F Antibody (NBP2-50392) (0)

There are no reviews for Respiratory Syncytial Virus Glycoprotein F Antibody (NBP2-50392). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Respiratory Syncytial Virus Glycoprotein F Antibody (NBP2-50392) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Array Products

Blogs on Respiratory Syncytial Virus Glycoprotein F

There are no specific blogs for Respiratory Syncytial Virus Glycoprotein F, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Respiratory Syncytial Virus Glycoprotein F Antibody (11-3-A3) and receive a gift card or discount.