Respiratory Syncytial Virus Glycoprotein F Antibody (11-3-A3) [Alexa Fluor® 532]


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Product Details

Reactivity ViSpecies Glossary
Applications WB, ELISA, ICC/IF
Alexa Fluor 532

Respiratory Syncytial Virus Glycoprotein F Antibody (11-3-A3) [Alexa Fluor® 532] Summary

Gradient-purified RSF-44 virus (subgroup A) UV inactivated for 20 minutes at 20C
This antibody has a high neutralising activity; 90% plaque neutralization titre of 103 (Gimenez et al., 1996). This property makes it potentially useful for the preparation of reagents for prevention and/or for therapeutic use in managing RS virus infections (for example, vaccines or new-generation man-made antibodies).This antibody reacts with the fusion protein F (also named VP70 or F0 protein) and specifically to a subunit of the F protein, F1 (also named 48kDa). The antibody reacts with the RS virus F1 protein from both subgroups A and B of the virus.New-generation man-made antibodies, based on the 11-3-A3 antibody, could complement the effectiveness of polivizumab (Synagis), which is used to prevent but not treat established RS virus infections (Nature Biotechnology, 2013: 31, 952).Significantly, there was no evidence of antibody dependant enhancement of RS virus infection in vitro for the 11-3-A3 antibody. The enhancing activity was found for other antibodies to the F protein (Gimenez et al 1996).
IgG1 Kappa
Protein G purified
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  • Western Blot
  • Immunocytochemistry/Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Protein G purified


Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-50392AF350
Alexa Fluor 405 NBP2-50392AF405
Alexa Fluor 488 NBP2-50392AF488
Alexa Fluor 532 NBP2-50392AF532
Alexa Fluor 594 NBP2-50392AF594
Alexa Fluor 647 NBP2-50392AF647
Alexa Fluor 700 NBP2-50392AF700
Alexa Fluor 750 NBP2-50392AF750
Biotin NBP2-50392B
DyLight 350 NBP2-50392UV
DyLight 405 NBP2-50392V
DyLight 488 NBP2-50392G
DyLight 550 NBP2-50392R
DyLight 594 NBP2-50392DL594
DyLight 650 NBP2-50392C
DyLight 680 NBP2-50392FR
DyLight 755 NBP2-50392IR
FITC NBP2-50392F
HRP NBP2-50392H
Janelia Fluor 549 NBP2-50392JF549
Janelia Fluor 646 NBP2-50392JF646

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